Anteroposterior (AP) patterning of the vertebrate neural plate is initiated during gastrulation
and is regulated by Spemann's organizer and its derivatives. The prevailing model for AP …

XWnt-5A, a member of the nontransforming Wnt-5A class of Wnt ligands, is required for
convergent extension movements in Xenopus embryos. XWnt-5A knockdown phenocopies …

We analyzed the spatiotemporal pattern of expression of 15 transcription factors (Six1, Six4,
Eya1, Sox3, Sox2, Pax6, Pax3, Pax2, Pax8, Dlx3, Msx1, FoxI1c, Tbx2, Tbx3, Xiro1) during …

How and when the vertebrate endoderm is first subdivided into discrete progenitor cell
populations that will give rise to the different major organs, including pancreas and liver, are …

Lrp5/6 are crucial coreceptors for Wnt/β-catenin signaling, a pathway biochemically distinct
from noncanonical Wnt signaling pathways. Here, we examined the possible participation of …

Convergent extension movements occur ubiquitously in animal development. This special
type of cell movement is controlled by the Wnt/planar cell polarity (PCP) pathway. Here we …

The competence of a cell to respond to the signalling molecule retinoic acid (RA) is thought
to depend largely on its repertoire of cognate zinc finger nuclear receptors. XCYP26 is an …

Cranial neural crest (CNC) cells migrate extensively, typically in a pattern of cell streams. In
Xenopus, these cells express the adhesion molecule Xcadherin-11 (Xcad-11) as they begin …

ABSTRACT Dickkopf1 (dkk1) encodes a secreted WNT inhibitor expressed in Spemann's
organizer, which has been implicated in head induction in Xenopus. Here we have analyzed …

Germ plasm formation is considered to define the first step in germ cell development.
Xenopus Dead end represents a germ plasm specific transcript that is homologous to the …