[HTML][HTML] Circulating RNAs in prostate cancer patients
Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …
The influence of biological and lifestyle factors on circulating cell-free DNA in blood plasma
Research and clinical use of circulating cell-free DNA (cirDNA) is expanding rapidly;
however, there remain large gaps in our understanding of the influence of lifestyle and …
however, there remain large gaps in our understanding of the influence of lifestyle and …
Current challenges and best practices for cell-free long RNA biomarker discovery
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
Plasma cell‐free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case‐control study and an ovarian cancer screening trial
Abstract Analysis of cell‐free DNA methylation (cfDNAme), alone or combined with CA125,
could help to detect ovarian cancers earlier and may reduce mortality. We assessed …
could help to detect ovarian cancers earlier and may reduce mortality. We assessed …
[HTML][HTML] A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics
C Grätz, M Schuster, F Brandes, AS Meidert… - Molecular Aspects of …, 2024 - Elsevier
Extracellular vesicles are shed by every cell type and can be found in any biofluid. They
contain different molecules that can be utilized as biomarkers, including several RNA …
contain different molecules that can be utilized as biomarkers, including several RNA …
Integrated analysis of circulating cell free nucleic acids for cancer genotyping and immune phenotyping of tumor microenvironment
M Chaddha, H Rai, R Gupta, D Thakral - Frontiers in Genetics, 2023 - frontiersin.org
The circulating cell-free nucleic acids (ccfNAs) consist of a heterogenous cocktail of both
single (ssNA) and double-stranded (dsNA) nucleic acids. These ccfNAs are secreted into the …
single (ssNA) and double-stranded (dsNA) nucleic acids. These ccfNAs are secreted into the …
Age-related changes in antigen-specific natural antibodies are influenced by sex
SE Webster, NL Tsuji, MJ Clemente… - Frontiers in …, 2023 - frontiersin.org
Introduction Natural antibody (NAb) derived from CD5+ B-1 cells maintains tissue
homeostasis, controls inflammation, aids in establishing long-term protective responses …
homeostasis, controls inflammation, aids in establishing long-term protective responses …
Low fetal fraction in obese women at first trimester cell‐free DNA based prenatal screening is not accompanied by differences in total cell‐free DNA
R Shree, TR Kolarova, HJ MacKinnon… - Prenatal …, 2021 - Wiley Online Library
Objective Reasons for first trimester noninvasive prenatal screening (NIPS) test failure in
obese women remain elusive. As dilution from maternal sources may be explanatory, we …
obese women remain elusive. As dilution from maternal sources may be explanatory, we …
Quantitative Analysis of Cell-Free RNA at Attomolar Level Using CRISPR/Cas Digital Imaging Platform
Y Li, F Quan, Y Wu, Y Zhang, R Xu, Y Wu… - Analytical …, 2024 - ACS Publications
Quantitative analysis of cell-free RNA (cfRNA) in plasma sample can be used for screening,
diagnosing, and prognosticating of multiple diseases. Here, we report a quantitative …
diagnosing, and prognosticating of multiple diseases. Here, we report a quantitative …
A review on cell-Free RNA Profiling: insights into metabolic diseases and predictive value for bariatric surgery outcomes
M Mareboina, E Deng, I Mouratidis, NS Yee… - Molecular …, 2024 - Elsevier
The advent of liquid biopsies presents a novel, minimally invasive methodology for the
detection of disease biomarkers, offering a significant advantage over traditional biopsy …
detection of disease biomarkers, offering a significant advantage over traditional biopsy …