Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Today, adoptive cell therapy has many successes in cancer therapy, and this subject is
brilliant in using chimeric antigen receptor T cells. The CAR T cell therapy, with its FDA …

Neutrophils are abundant immune cells in the circulation and frequently infiltrate tumors in
substantial numbers. However, their precise functions in different cancer types remain …

CRISPR-Cas9-mediated homology-directed repair (HDR) is a versatile platform for creating
precise site-specific DNA insertions, deletions, and substitutions. These precise edits are …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

With the development of nanotechnology, nanoparticles (NPs) have shown broad prospects
as drug delivery vehicles. However, they exhibit certain limitations, including low …

In recent years, advancements in microbial sequencing technology have sparked an
increasing interest in the bacteria residing within solid tumors and its distribution and …

The blood-brain barrier (BBB) and tumor microenvironment of glioma limit the efficacies of
various therapies, and thus glioma treatment is challenging. We herein report …

Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

The progress of precision oncology medicine is always limited by the tumor off‐targeting, the
drug side effects, and the treatment inefficiency due to the complex and ever‐changing …