Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

Normal aging results in subtle changes both in ACTH and cortisol secretion. Most notable is
the general increase in mean daily serum cortisol levels in the elderly, without a noteworthy …

This review aims at describing the beneficial properties of melatonin related to its antioxidant
effects. Oxidative stress, ie, an imbalance between the production of reactive oxygen …

Experimental studies have proven that melatonin has many beneficial pleiotropic actions.
The aim of this study was to assess melatonin efficacy in patients with metabolic syndrome …

Oxidative stress plays a key role in the pathogenesis of aging and many metabolic diseases;
therefore, an effective antioxidant therapy would be of great importance in these …

This review summarizes the metabolism, secretion, regulation and sites of action of
melatonin. An updated description of the melatonin receptors, including their signal …

Mucositis is a common and distressing side effect of chemotherapy or radiotherapy that has
potentially severe consequences, and no treatment is available. The purpose of this study …

Background Melatonin is a hormone that regulates circadian rhythm, and its levels decline
with age. As melatonin levels decrease, older adults are prone to develop disorders related …

Obesity is one of the major global health problems. Melatonin deficiency has been
demonstrated to correlate with obesity. The aim of the study was to estimate the effect of …

Obesity, the global epidemic health problem, results in chronic disorders. Melatonin
supplementation may prevent the adverse health consequences of obesity. The aim of this …