Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Leptin, cardiovascular diseases and type 2 diabetes mellitus

N Katsiki, DP Mikhailidis, M Banach - Acta Pharmacologica Sinica, 2018 - nature.com
Leptin, an adipokine that is implicated in the control of food intake via appetite suppression,
may also stimulate oxidative stress, inflammation, thrombosis, arterial stiffness …

The macrophage switch in obesity development

A Castoldi, C Naffah de Souza, NOS Câmara… - Frontiers in …, 2016 - frontiersin.org
Immune cell infiltration in (white) adipose tissue (AT) during obesity is associated with the
development of insulin resistance. In AT, the main population of leukocytes are …

Impact of diabetes in patients diagnosed with COVID-19

M Abu-Farha, F Al-Mulla, TA Thanaraj… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a disease caused by the coronavirus SARS-CoV-2 (Severe Acute Respiratory
Syndrome Coronavirus-2), known as a highly contagious disease, currently affecting more …

Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

N Sallam, I Laher - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

[HTML][HTML] Adipose tissue in control of metabolism

L Luo, M Liu - Journal of endocrinology, 2016 - joe.bioscientifica.com
Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

Adipose tissue-derived signatures for obesity and type 2 diabetes: adipokines, batokines and microRNAs

MW Lee, M Lee, KJ Oh - Journal of clinical medicine, 2019 - mdpi.com
Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride

L Zhang, C Chen, N Zhou, Y Fu, X Cheng - Clinica chimica acta, 2019 - Elsevier
Background Asprosin has been identified as a novel hormone enriched in white adipose
tissue and is pathologically increased in insulin-resistant mice and humans. However …

Adiponectin, lipids and atherosclerosis

N Katsiki, C Mantzoros… - Current opinion in …, 2017 - journals.lww.com
Based on available data, adiponectin represents a multifaceted biomarker that may
beneficially affect atherosclerosis, inflammation and insulin resistance pathways. However …

Role of inflammation in diabetic cardiomyopathy

P Ramesh, JL Yeo, EM Brady… - … in Endocrinology and …, 2022 - journals.sagepub.com
The prevalence of type 2 diabetes (T2D) has reached a pandemic scale. Systemic chronic
inflammation dominates the diabetes pathophysiology and has been implicated as a causal …