Host–microbiota interactions in immune-mediated diseases

WE Ruff, TM Greiling, MA Kriegel - Nature Reviews Microbiology, 2020 - nature.com
Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …

[HTML][HTML] Effect of cigarette smoke on gut microbiota: state of knowledge

X Gui, Z Yang, MD Li - Frontiers in Physiology, 2021 - frontiersin.org
Cigarette smoke is a representative source of toxic chemical exposures to humans, and the
adverse consequences of cigarette smoking are mediated by its effect on both neuronal and …

Lactobacillus johnsonii alleviates colitis by TLR1/2-STAT3 mediated CD206+ macrophagesIL-10 activation

DJC Jia, QW Wang, YY Hu, JM He, QW Ge, YD Qi… - Gut …, 2022 - Taylor & Francis
Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …

Investigating causality with fecal microbiota transplantation in rodents: applications, recommendations and pitfalls

CE Gheorghe, NL Ritz, JA Martin, HR Wardill… - Gut …, 2021 - Taylor & Francis
In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis

K Miyamoto, T Sujino, Y Harada, H Ashida… - Cell Reports, 2023 - cell.com
The intricate interplay between gut microbes and the onset of experimental autoimmune
encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable …

The interaction of intestinal microbiota and innate lymphoid cells in health and disease throughout life

SC Ganal‐Vonarburg, CU Duerr - Immunology, 2020 - Wiley Online Library
Immunity is shaped by commensal microbiota. From early life onwards, microbes colonize
mucosal surfaces of the body and thereby trigger the establishment of immune homeostasis …

[HTML][HTML] Treatment of ulcerative colitis with Wu-Mei-Wan by inhibiting intestinal inflammatory response and repairing damaged intestinal mucosa

S Yan, P Wang, H Wei, R Jia, M Zhen, Q Li, C Xue, J Li - Phytomedicine, 2022 - Elsevier
Abstract Background Wu-Mei-Wan (WMW), a traditional Chinese medicine, has been
applied in the treatment of gastrointestinal diseases with long-term diarrhea and …

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway

Y Zhang, Z Zha, W Shen, D Li, N Kang, Z Chen, Y Liu… - Chinese Medicine, 2021 - Springer
Background Despite the increased morbidity of ulcerative colitis (UC) in the developing
countries, available treatments remain unsatisfactory. Therefore, it is urgent to discover more …

Potential roles of inflammasomes in the pathophysiology of Psoriasis: A comprehensive review

A Shahi, S Afzali, A Amirzargar, P Mohaghegh… - Molecular …, 2023 - Elsevier
Psoriasis is an inflammatory skin disease whose pathophysiology is attributed to both innate
and adaptive immune cells and molecules. Despite the crucial roles of the immune system in …

Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice

H Shinno-Hashimoto, Y Hashimoto, Y Wei, L Chang… - Scientific Reports, 2021 - nature.com
Psoriasis is a chronic, inflammatory skin disease. Although the precise etiology of psoriasis
remains unclear, gut–microbiota axis might play a role in the pathogenesis of the disease …