Heat shock proteins 90 (Hsp90) and 70 (Hsp70) are two families of highly conserved ATP-
dependent molecular chaperones that fold and remodel proteins. Both are important …

I. Introduction II. 9S Receptors A. Estrogen receptors (ERs) B. Progesterone receptors (PRs)
C. Androgen receptors (ARs) D. Glucocorticoid receptors (GRs) E. Mineralocorticoid …

The 90-kDa molecular chaperone family (which comprises, among other proteins, the 90-
kDa heat-shock protein, hsp90 and the 94-kDa glucose-regulated protein, grp94, major …

Heat-shock protein 90 (Hsp90) is an abundant and highly conserved molecular chaperone
that is essential for viability in eukaryotes. Hsp90 fulfills a housekeeping function in …

The highly conserved heat shock proteins (HSPs) accumulate in cells exposed to heat and a
variety of other stressful stimuli. HSPs, which function mainly as molecular chaperones …

Stress or heat shock proteins (HSPs) are the most conserved proteins present in both
prokaryotes and eukaryotes. Their expression is induced in response to a wide variety of …

HIF-1α is a normally labile proangiogenic transcription factor that is stabilized and activated
in hypoxia. Although the von Hippel Lindau (VHL) gene product, the ubiquitin ligase …

Introduction• Main HSPs• HSPs, cell signalling and apoptosis‐HSPs' targets in upstream
signalling pathways‐HSPs' targets at the mitochondrial level‐HSPs' targets at the post …

The heat shock protein (Hsp) 90 chaperone machinery regulates the activity of hundreds of
client proteins in the eukaryotic cytosol. It undergoes large conformational changes between …

The cellular stress response protects organisms from damage resulting from exposure to a
wide variety of stressors, including elevated temperatures, ultraviolet (UV) light, trace metals …