Antimicrobial peptides: the Achilles' heel of antibiotic resistance?

A Lewies, LH Du Plessis, JF Wentzel - Probiotics and antimicrobial …, 2019 - Springer
Antibiotic resistance is an imminent threat to the effective treatment of bacterial infections,
and alternative antibiotic strategies are urgently required. The golden epoch of antibiotics is …

Tuning of a membrane-perforating antimicrobial peptide to selectively target membranes of different lipid composition

CH Chen, CG Starr, S Guha, WC Wimley… - The Journal of …, 2021 - Springer
The use of designed antimicrobial peptides as drugs has been impeded by the absence of
simple sequence-structure–function relationships and design rules. The likely cause is that …

Anti-fungal Effects and Mechanisms of Action of Wasp Venom-Derived Peptide Mastoparan-VT1 Against Candida albicans

M Memariani, H Memariani, Z Poursafavi… - International Journal of …, 2022 - Springer
Candida albicans, an opportunistic yeast pathogen, is equipped with a plethora of virulence
attributes such as yeast-to-hyphae transition, secreted enzymes, tissue adhesion, and …

Identification of Antimicrobial Peptides from Novel Lactobacillus fermentum Strain

AS Pavlova, GD Ozhegov, GP Arapidi, IO Butenko… - The Protein …, 2020 - Springer
Antimicrobial peptides (AMPs) are natural antagonistic tools of many bacteria and are
considered as attractive antimicrobial agents for the treatment of bacteria with multidrug …

Anticandidal activity and mechanism of action of several cationic chimeric antimicrobial peptides

M Memariani, H Memariani, H Moravvej… - International Journal of …, 2023 - Springer
Antimicrobial peptides (AMPs) have recently been the subject of extensive research in both
academia and commercial sectors because of their rapid, broad-spectrum microbicidal …

Machine Learning Accelerates De Novo Design of Antimicrobial Peptides

K Yin, W Xu, S Ren, Q Xu, S Zhang, R Zhang… - Interdisciplinary …, 2024 - Springer
Efficient and precise design of antimicrobial peptides (AMPs) is of great importance in the
field of AMP development. Computing provides opportunities for peptide de novo design. In …

[HTML][HTML] Identification of a novel antibacterial protein from hemolymph of freshwater zooplankton Mesocyclops leuckarti

V Praveena, S Venkatalakshmi, NS Alharbi… - Saudi Journal of …, 2020 - Elsevier
Bacterial infections are the most important problem of health care worldwide. The
hemolymph antibacterial proteins of Mesocyclops leuckarti was isolated for the first time and …