Understanding the gut microbiota and sarcopenia: a systematic review

C Liu, WH Cheung, J Li, SKH Chow… - Journal of cachexia …, 2021 - Wiley Online Library
Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia

S Peixoto da Silva, JMO Santos… - Journal of cachexia …, 2020 - Wiley Online Library
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Microbiota: a key orchestrator of cancer therapy

S Roy, G Trinchieri - Nature Reviews Cancer, 2017 - nature.com
The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

Cancer cachexia: understanding the molecular basis

JM Argilés, S Busquets, B Stemmler… - Nature Reviews …, 2014 - nature.com
Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects
around 50–80% of cancer patients, depending on the tumour type, and that leads to …

Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

[HTML][HTML] Microbiota-gut-brain axis: modulator of host metabolism and appetite

M Van de Wouw, H Schellekens, TG Dinan… - The Journal of nutrition, 2017 - Elsevier
The gut harbors an enormous diversity of microbes that are essential for the maintenance of
homeostasis in health and disease. A growing body of evidence supports the role of this …

Understanding cachexia as a cancer metabolism syndrome

PE Porporato - Oncogenesis, 2016 - nature.com
Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …

Inter-tissue communication in cancer cachexia

JM Argilés, B Stemmler, FJ López-Soriano… - Nature Reviews …, 2019 - nature.com
Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis

WHW Tang, Z Wang, Y Fan, B Levison… - Journal of the American …, 2014 - jacc.org
Background: Altered intestinal function is prevalent in patients with heart failure (HF), but its
role in adverse outcomes is unclear. Objectives: This study investigated the potential …

[HTML][HTML] Fueling gut microbes: a review of the interaction between diet, exercise, and the gut microbiota in athletes

RL Hughes, HD Holscher - Advances in nutrition, 2021 - Elsevier
The athlete's goal is to optimize their performance. Towards this end, nutrition has been
used to improve the health of athletes' brains, bones, muscles, and cardiovascular system …