Bacteria predominantly exist as multicellular aggregates known as biofilms that are
associated with at least two thirds of all infections and exhibit increased adaptive resistance …

Treatment for cystic fibrosis (CF) has conventionally targeted downstream consequences of
the defect such as mucus plugging and infection. More recently, significant advances have …

Cationic antimicrobial peptides (CAMPs) are very promising in the treatment of multi-drug
resistant Pseudomonas aeruginosa lung infections experienced by cystic fibrosis (CF) …

Cystic fibrosis (CF) is a complex, potentially life-threatening disease that is most effectively
treated through the administration of antibiotics (eg, colistimethate sodium). Chronic …

Cystic fibrosis is a genetic disease that results in progressive multi-organ manifestations with
predominance in the respiratory and gastrointestinal systems. The significant morbidity and …

The use of inhaled antibiotics was initially almost exclusively confined to patients with cystic
fibrosis (CF). However, it has been extended in recent decades to patients with non-CF …

Biofilm-residing bacteria embedded in an extracellular matrix are protected from diverse
physicochemical insults. In addition to the general recalcitrance of biofilm bacteria, high …

Administration of medications via aerosolization is potentially an ideal strategy to treat
airway diseases. This delivery method ensures high concentrations of the medication in the …

Antimicrobial peptides (AMPs) are being intensively investigated as they are considered
promising alternatives to antibiotics where their clinical efficacy is dwindling due to the …

Introduction: The most widely used pharmacological treatment for Parkinson's disease is
levodopa, the precursor for dopamine formation in the brain. Over time, the effectiveness of …