Conquering the hypoxia limitation for photodynamic therapy

Y Wan, LH Fu, C Li, J Lin, P Huang - Advanced Materials, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

[HTML][HTML] Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes

NJ Hogrebe, M Ishahak, JR Millman - Cell Stem Cell, 2023 - cell.com
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models

P Jain, H Kathuria, N Dubey - Biomaterials, 2022 - Elsevier
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …

Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy

H Lin, Y Chen, J Shi - Chemical Society Reviews, 2018 - pubs.rsc.org
Tumour chemotherapy employs highly cytotoxic chemodrugs, which kill both cancer and
normal cells by cellular apoptosis or necrosis non-selectively. Catalysing/triggering the …

Potential applications of nanomaterials and technology for diabetic wound healing

Q Bai, K Han, K Dong, C Zheng, Y Zhang… - International journal …, 2020 - Taylor & Francis
Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …

Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Gas-mediated cancer bioimaging and therapy

L Chen, SF Zhou, L Su, J Song - ACS nano, 2019 - ACS Publications
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …

[HTML][HTML] Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research

TL Place, FE Domann, AJ Case - Free Radical Biology and Medicine, 2017 - Elsevier
Molecular oxygen is one of the most important variables in modern cell culture systems.
Fluctuations in its concentration can affect cell growth, differentiation, signaling, and free …

Nanocatalysts-augmented Fenton chemical reaction for nanocatalytic tumor therapy

X Qian, J Zhang, Z Gu, Y Chen - Biomaterials, 2019 - Elsevier
It is the challenging goal in cancer biomedicine to search novel cancer-therapeutic modality
with concurrent high therapeutic efficiency on combating cancer and low side effects to …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …