Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
[HTML][HTML] Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes
NJ Hogrebe, M Ishahak, JR Millman - Cell Stem Cell, 2023 - cell.com
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …
Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy
Tumour chemotherapy employs highly cytotoxic chemodrugs, which kill both cancer and
normal cells by cellular apoptosis or necrosis non-selectively. Catalysing/triggering the …
normal cells by cellular apoptosis or necrosis non-selectively. Catalysing/triggering the …
Potential applications of nanomaterials and technology for diabetic wound healing
Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …
patients to an environment with a high risk of infection. This article has summarized current …
Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …
strong resistance to therapy, leading to the poor prognosis in several cancer types …
Gas-mediated cancer bioimaging and therapy
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
[HTML][HTML] Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research
Molecular oxygen is one of the most important variables in modern cell culture systems.
Fluctuations in its concentration can affect cell growth, differentiation, signaling, and free …
Fluctuations in its concentration can affect cell growth, differentiation, signaling, and free …
Nanocatalysts-augmented Fenton chemical reaction for nanocatalytic tumor therapy
It is the challenging goal in cancer biomedicine to search novel cancer-therapeutic modality
with concurrent high therapeutic efficiency on combating cancer and low side effects to …
with concurrent high therapeutic efficiency on combating cancer and low side effects to …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …