ATP synthase FOF1 structure, function, and structure-based drug design

AV Vlasov, SD Osipov, NA Bondarev… - Cellular and Molecular …, 2022 - Springer
ATP synthases are unique rotatory molecular machines that supply biochemical reactions
with adenosine triphosphate (ATP)—the universal “currency”, which cells use for synthesis …

Rotational Mechanism of FO Motor in the F-Type ATP Synthase Driven by the Proton Motive Force

S Kubo, S Takada - Frontiers in Microbiology, 2022 - frontiersin.org
In FOF1 ATP synthase, driven by the proton motive force across the membrane, the FO
motor rotates the central rotor and induces conformational changes in the F1 motor, resulting …

Structure and dynamics of the SARS‐CoV‐2 envelope protein monomer

A Kuzmin, P Orekhov, R Astashkin… - Proteins: Structure …, 2022 - Wiley Online Library
Coronaviruses, especially severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2),
present an ongoing threat to human wellbeing. Consequently, elucidation of molecular …

Structural insights into light-driven anion pumping in cyanobacteria

R Astashkin, K Kovalev, S Bukhdruker… - Nature …, 2022 - nature.com
Transmembrane ion transport is a key process in living cells. Active transport of ions is
carried out by various ion transporters including microbial rhodopsins (MRs). MRs perform …

Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization

RK Flygaard, A Mühleip, V Tobiasson… - Nature …, 2020 - nature.com
Mitochondrial ATP synthases form functional homodimers to induce cristae curvature that is
a universal property of mitochondria. To expand on the understanding of this fundamental …

Functions, working mechanisms, and regulation of rotary ATPases and Ductin proteins

T Páli, B Feniouk, S Wilkens - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
The rotary mechanism of the ion-transporting F-, V-and A-type ATPases is of great interest to
the molecular bio-sciences. Connecting the regulation of their rotation-coupled catalysis …

High-throughput algorithm predicts F-Type ATP synthase rotor ring stoichiometries of 8 to 27 protomers

S Osipov, E Zinoviev, A Anuchina, A Kuzmin… - bioRxiv, 2024 - biorxiv.org
ATP synthases are large enzymes present in every living cell. They consist of a
transmembrane and a soluble domain, each comprising multiple subunits. The …

[PDF][PDF] New structural insights in chloroplast F1FO-ATP synthases

A Vlasov - 2021 - scholar.archive.org
ATP synthase is a unique molecular machine that produces the energy-rich molecule
adenosine triphosphate (ATP), which is necessary for numerous biochemical reactions in …