Bleeding and Thrombosis: Insights into Pathophysiology of Bothrops Venom-Related Hemostasis Disorders

S Larréché, JP Chippaux, L Chevillard… - International Journal of …, 2021 - mdpi.com
Toxins from Bothrops venoms targeting hemostasis are responsible for a broad range of
clinical and biological syndromes including local and systemic bleeding, incoagulability …

Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology

JS Cavalcante, DEG de Almeida… - International Journal of …, 2023 - mdpi.com
Snakebite envenoming represents a major health problem in tropical and subtropical
countries. Considering the elevated number of accidents and high morbidity and mortality …

Incidence and mortality due to snakebite in the Americas

JP Chippaux - PLoS neglected tropical diseases, 2017 - journals.plos.org
Background Better knowledge of the epidemiological characteristics of snakebites could
help to take measures to improve their management. The incidence and mortality of …

Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation

C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

Neurological complications of venomous snake bites: a review

OH Del Brutto, VJ Del Brutto - Acta Neurologica Scandinavica, 2012 - Wiley Online Library
Del Brutto OH, Del Brutto VJ. Neurological complications of venomous snake bites: a review.
Acta Neurol Scand: 2012: 125: 363–372.© 2011 John Wiley & Sons A/S. Abstract–Snake …

Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a …

JM Gutiérrez, L Sanz, J Escolano… - Journal of proteome …, 2008 - ACS Publications
The venom proteomes of the snakes Bothrops caribbaeus and Bothrops lanceolatus,
endemic to the Lesser Antillean islands of Saint Lucia and Martinique, respectively, were …

Antivenom for neuromuscular paralysis resulting from snake envenoming

A Silva, WC Hodgson, GK Isbister - Toxins, 2017 - mdpi.com
Antivenom therapy is currently the standard practice for treating neuromuscular dysfunction
in snake envenoming. We reviewed the clinical and experimental evidence-base for the …

Reappraisal of Vipera aspis Venom Neurotoxicity

E Ferquel, L De Haro, V Jan, I Guillemin, S Jourdain… - PloS one, 2007 - journals.plos.org
Background The variation of venom composition with geography is an important aspect of
intraspecific variability in the Vipera genus, although causes of this variability remain …

Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics

JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura… - Toxicon, 2013 - Elsevier
The assessment of the capacity of antivenoms to neutralize the lethal activity of snake
venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely …

Bothrops venom-induced hemostasis disorders in the rat: Between Scylla and Charybdis

S Larréché, L Chevillard, G Jourdi… - PLOS Neglected …, 2023 - journals.plos.org
Hemostasis impairment represents the most threatening consequence of Viperidae
envenoming, notably with Bothrops genus. In the French departments of America, B. atrox …