Circadian rhythm and disease: Relationship, new insights, and future perspectives
AR Neves, T Albuquerque, T Quintela… - Journal of cellular …, 2022 - Wiley Online Library
The circadian system is responsible for internal functions and regulation of the organism
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …
[HTML][HTML] Molecular interactions between components of the circadian clock and the immune system
S Hergenhan, S Holtkamp, C Scheiermann - Journal of molecular biology, 2020 - Elsevier
The immune system is under control of the circadian clock. Many of the circadian rhythms
observed in the immune system originate in direct interactions between components of the …
observed in the immune system originate in direct interactions between components of the …
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
A variety of innate immune responses and functions are dependent on time of day, and
many inflammatory conditions are associated with dysfunctional molecular clocks within …
many inflammatory conditions are associated with dysfunctional molecular clocks within …
Asthma and obstructive sleep apnoea in adults and children–an up-to-date review
Obstructive sleep apnoea (OSA) and asthma are two common respiratory disorders in
children and adults. Apart from common risk factors, such as obesity, gastroesophageal …
children and adults. Apart from common risk factors, such as obesity, gastroesophageal …
Adaptive immunity, chronic inflammation and the clock
KJ Gray, JE Gibbs - Seminars in Immunopathology, 2022 - Springer
The adaptive arm of the immune system facilitates recognition of specific foreign pathogens
and, via the action of T and B lymphocytes, induces a fine-tuned response to target the …
and, via the action of T and B lymphocytes, induces a fine-tuned response to target the …
[HTML][HTML] Time-of-day-dependent trafficking and function of leukocyte subsets
The number of leukocytes circulating in blood in mammals is under circadian control (ie,∼
24h). We summarize here latest findings on the mechanisms governing leukocyte migration …
24h). We summarize here latest findings on the mechanisms governing leukocyte migration …
Circadian molecular clock disruption in chronic pulmonary diseases
The circadian clock is the biochemical oscillator with a near 24-h period that is responsible
for generating the circadian rhythms in peripheral organs including the lung. Mounting …
for generating the circadian rhythms in peripheral organs including the lung. Mounting …
Ozone-induced oxidative stress, neutrophilic airway inflammation, and glucocorticoid resistance in asthma
Despite recent advances in using biologicals that target Th2 pathways, glucocorticoids form
the mainstay of asthma treatment. Asthma morbidity and mortality remain high due to the …
the mainstay of asthma treatment. Asthma morbidity and mortality remain high due to the …
Circadian immune circuits
M Palomino-Segura, A Hidalgo - Journal of Experimental Medicine, 2020 - rupress.org
Immune responses are gated to protect the host against specific antigens and microbes, a
task that is achieved through antigen-and pattern-specific receptors. Less appreciated is that …
task that is achieved through antigen-and pattern-specific receptors. Less appreciated is that …
Sleep and asthma
J Kavanagh, DJ Jackson, BD Kent - Current opinion in pulmonary …, 2018 - journals.lww.com
Sleep and asthma : Current Opinion in Pulmonary Medicine Sleep and asthma : Current Opinion
in Pulmonary Medicine Log in or Register Subscribe to journalSubscribe Get new issue …
in Pulmonary Medicine Log in or Register Subscribe to journalSubscribe Get new issue …