Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments
R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
Branched-chain amino acids: catabolism in skeletal muscle and implications for muscle and whole-body metabolism
G Mann, S Mora, G Madu, OAJ Adegoke - Frontiers in Physiology, 2021 - frontiersin.org
Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body
anabolism and energy homeostasis. They also serve as signaling molecules, for example …
anabolism and energy homeostasis. They also serve as signaling molecules, for example …
The critical role of the branched chain amino acids (BCAAs) catabolism-regulating enzymes, branched-chain aminotransferase (BCAT) and branched-chain α-keto …
A Dimou, V Tsimihodimos, E Bairaktari - International Journal of …, 2022 - mdpi.com
Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …
Branched chain amino acids, aging and age-related health
Branched chain amino acids (BCAA: leucine, valine, isoleucine) have key physiological
roles in the regulation of protein synthesis, metabolism, food intake and aging. Many studies …
roles in the regulation of protein synthesis, metabolism, food intake and aging. Many studies …
Prebiotic and probiotic modulation of the microbiota–gut–brain axis in depression
DE Radford-Smith, DC Anthony - Nutrients, 2023 - mdpi.com
Emerging evidence demonstrates that alterations to the gut microbiota can affect mood,
suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of …
suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of …
Why are branched-chain amino acids increased in starvation and diabetes?
M Holeček - Nutrients, 2020 - mdpi.com
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are increased in
starvation and diabetes mellitus. However, the pathogenesis has not been explained. It has …
starvation and diabetes mellitus. However, the pathogenesis has not been explained. It has …
[HTML][HTML] Advances in multi-omics study of biomarkers of glycolipid metabolism disorder
X Fang, R Miao, J Wei, H Wu, J Tian - Computational and Structural …, 2022 - Elsevier
Glycolipid metabolism disorder are major threats to human health and life. Genetic,
environmental, psychological, cellular, and molecular factors contribute to their …
environmental, psychological, cellular, and molecular factors contribute to their …
[HTML][HTML] Tea polyphenol–gut microbiota interactions: Hints on improving the metabolic syndrome in a multi-element and multi-target manner
H Ma, Y Hu, B Zhang, Z Shao, E Roura… - Food Science and Human …, 2022 - Elsevier
The metabolic syndrome (MS) has become one of the main problems in public health. Tea
polyphenols (TPs), the main bioactive components of tea, has been claimed to have the …
polyphenols (TPs), the main bioactive components of tea, has been claimed to have the …
Omics biomarkers in obesity: novel etiological insights and targets for precision prevention
K Aleksandrova, C Egea Rodrigues, A Floegel… - Current obesity …, 2020 - Springer
Abstract Purpose of Review Omics-based technologies were suggested to provide an
advanced understanding of obesity etiology and its metabolic consequences. This review …
advanced understanding of obesity etiology and its metabolic consequences. This review …
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
Background Obesity predisposes individuals to multiple cardiometabolic disorders,
including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat …
including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat …