The log-dynamic brain: how skewed distributions affect network operations

G Buzsáki, K Mizuseki - Nature Reviews Neuroscience, 2014 - nature.com
We often assume that the variables of functional and structural brain parameters—such as
synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural …

CA1 pyramidal cell diversity enabling parallel information processing in the hippocampus

I Soltesz, A Losonczy - Nature neuroscience, 2018 - nature.com
Hippocampal network operations supporting spatial navigation and declarative memory are
traditionally interpreted in a framework where each hippocampal area, such as the dentate …

Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons

MS Cembrowski, N Spruston - Nature Reviews Neuroscience, 2019 - nature.com
The mechanistic operation of brain regions is often interpreted by partitioning constituent
neurons into 'cell types'. Historically, such cell types were broadly defined by their …

[HTML][HTML] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1

NB Danielson, JD Zaremba, P Kaifosh, J Bowler… - Neuron, 2016 - cell.com
The mammalian hippocampus is critical for spatial information processing and episodic
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …

Spatial gene-expression gradients underlie prominent heterogeneity of CA1 pyramidal neurons

MS Cembrowski, JL Bachman, L Wang, K Sugino… - Neuron, 2016 - cell.com
Tissue and organ function has been conventionally understood in terms of the interactions
among discrete and homogeneous cell types. This approach has proven difficult in …

Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations

T Klausberger, P Somogyi - Science, 2008 - science.org
In the cerebral cortex, diverse types of neurons form intricate circuits and cooperate in time
for the processing and storage of information. Recent advances reveal a spatiotemporal …

How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

[HTML][HTML] Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells

SH Lee, I Marchionni, M Bezaire, C Varga, N Danielson… - Neuron, 2014 - cell.com
CA1 pyramidal cells (PCs) are not homogeneous but rather can be grouped by molecular,
morphological, and functional properties. However, less is known about synaptic sources …

Hippocampal CA1 pyramidal cells form functionally distinct sublayers

K Mizuseki, K Diba, E Pastalkova, G Buzsáki - Nature neuroscience, 2011 - nature.com
Hippocampal CA1 pyramidal neurons have frequently been regarded as a homogeneous
cell population in biophysical, pharmacological and modeling studies. We found robust …

The corticohippocampal circuit, synaptic plasticity, and memory

J Basu, SA Siegelbaum - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Synaptic plasticity serves as a cellular substrate for information storage in the central
nervous system. The entorhinal cortex (EC) and hippocampus are interconnected brain …