microRNAs in action: biogenesis, function and regulation
Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …
years ago, a broad community of researchers was drawn to investigate the universe of small …
Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
Spatial imaging of glycoRNA in single cells with ARPLA
Little is known about the biological roles of glycosylated RNAs (glycoRNAs), a recently
discovered class of glycosylated molecules, because of a lack of visualization methods. We …
discovered class of glycosylated molecules, because of a lack of visualization methods. We …
RNA-based diagnostic markers discovery and therapeutic targets development in cancer
H Wang, Q Meng, J Qian, M Li, C Gu, Y Yang - Pharmacology & …, 2022 - Elsevier
The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …
treatment, and to provide novel insights into their clinical applications. RNAs, including …
The MicroRNA family gets wider: the IsomiRs classification and role
MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding RNAs and are
engaged in many cellular processes, including cell differentiation, development, and …
engaged in many cellular processes, including cell differentiation, development, and …
An overview of rational design of mRNA-based therapeutics and vaccines
KKW To, WCS Cho - Expert opinion on drug discovery, 2021 - Taylor & Francis
ABSTRACT Introduction Messenger RNA (mRNA)-based therapeutics and vaccines have
emerged as a disruptive new drug class for various applications, including regenerative …
emerged as a disruptive new drug class for various applications, including regenerative …
Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines
In recent years, the main quest of science has been the pioneering of the groundbreaking
biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids …
biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids …
An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses
SG Dosil, S Lopez-Cobo, A Rodriguez-Galan… - Elife, 2022 - elifesciences.org
Natural killer (NK) cells recognize and kill target cells undergoing different types of stress.
NK cells are also capable of modulating immune responses. In particular, they regulate T …
NK cells are also capable of modulating immune responses. In particular, they regulate T …