Genetic associations in classical hodgkin lymphoma: a systematic review and insights into susceptibility mechanisms

K Kushekhar, A van den Berg, I Nolte, B Hepkema… - … Biomarkers & Prevention, 2014 - AACR
Both targeted and genome-wide studies have revealed genetic associations for
susceptibility, prognosis, and treatment-induced secondary malignancies and toxicities in …

MiRNAs and miRNA polymorphisms modify drug response

MP Li, YD Hu, XL Hu, YJ Zhang, YL Yang… - International journal of …, 2016 - mdpi.com
Differences in expression of drug response-related genes contribute to inter-individual
variation in drugs' biological effects. MicroRNAs (miRNAs) are small noncoding RNAs …

Association of polymorphic variants of miRNA processing genes with larynx cancer risk in a polish population

E Osuch-Wojcikiewicz, A Bruzgielewicz… - BioMed Research …, 2015 - Wiley Online Library
Laryngeal cancer (LC) is one of the most prevalent types of head and neck cancer. An
increasing interest has been focused on the role of microRNA (miRNAs) in LC development …

Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer

T Xu, Z Liao, MS O'Reilly, LB Levy, JW Welsh… - Radiotherapy and …, 2014 - Elsevier
Background and purpose MicroRNAs (miRNAs) are small, highly conserved non-coding
RNAs that regulate many biological processes. We sought to investigate whether three …

Prognostic role of common microRNA polymorphisms in cancers: evidence from a meta-analysis

L Xia, Y Ren, X Fang, Z Yin, X Li, W Wu, P Guan… - PLoS …, 2014 - journals.plos.org
Background The morbidity and mortality of cancer increase remarkably every year. It's a
heavy burden for family and society. The detection of prognostic biomarkers can help to …

Genetic variability of micro RNA regulome in human

J Obsteter, P Dovc, T Kunej - Molecular Genetics & Genomic …, 2015 - Wiley Online Library
MicroRNAs are currently being extensively studied due to their important role as post‐
transcriptional regulators. During miRNA biogenesis, precursors undergo two cleavage …

MicroRNA polymorphisms as markers of risk, prognosis and treatment response in hematological malignancies

A Dzikiewicz-Krawczyk - Critical reviews in oncology/hematology, 2015 - Elsevier
MicroRNA dysregulation is a common event in hematological malignancies. Apart from
genomic and epigenetic alterations, miRNA networks may be disturbed by polymorphisms in …

Non-coding RNAs in Hodgkin lymphoma

A Cordeiro, M Monzó, A Navarro - International journal of molecular …, 2017 - mdpi.com
MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression by binding to
the 3'-UTR of their target genes, can act as oncogenes or tumor suppressors. Recently, other …

A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma

Y Xie, L Diao, L Zhang, C Liu, Z Xu, S Liu - Gene, 2014 - Elsevier
MicroRNA (miRNA), which plays an important role in tumorigenesis, can regulate post-
transcriptional gene expression by binding to the 3′ untranslated regions (3′-UTRs) of …

Association of polymorphisms at the microRNA binding site of the caprine KITLG 3′-UTR with litter size

X An, Y Song, S Bu, H Ma, K Gao, J Hou, S Wang… - Scientific Reports, 2016 - nature.com
This study identified three novel single nucleotide polymorphisms (SNPs)(c. 1389C> T, c.
1457A> C and c. 1520G> A) in the caprine KITLG 3′-UTR through DNA sequencing. The …