The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Nose to brain drug delivery is considered as a viable option to deliver various therapeutic
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …

Nucleic acid-based therapeutics, including the use of messenger RNA (mRNA) as a drug
molecule, has tremendous potential in the treatment of chronic diseases, such as age …

Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent
diseases ranging from cancer and Alzheimer's disease to COVID-19 with significant clinical …

The limitations of central nervous system (CNS) drug delivery conferred by the blood-brain
barrier (BBB) have been a significant obstacle in the development of large molecule …

Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

Background Cystatin SN (CST1) and cystatin SA (CST2) are cysteine protease inhibitors that
protect against allergen, viral, and bacterial proteases. Cystatins are overexpressed in the …

Nucleic acid therapeutics have emerged as one of the very advanced and efficacious
treatment approaches for debilitating health conditions, including those diseases affecting …

Central nervous system integrity is the state of brain functioning across sensory, cognitive,
emotional-social behaviors, and motor domains, allowing a person to realise his full …