Inflammation and liver cancer: molecular mechanisms and therapeutic targets
Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …
Decoding hepatocarcinogenesis from a noncoding RNAs perspective
MKA El‐Aziz, A Dawoud, CJ Kiriacos… - Journal of cellular …, 2023 - Wiley Online Library
Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …
Natural killer cells as key players of tumor progression and angiogenesis: old and novel tools to divert their pro-tumor activities into potent anti-tumor effects
Immune cells, as a consequence of their plasticity, can acquire altered phenotype/functions
within the tumor microenvironment (TME). Some of these aberrant functions include …
within the tumor microenvironment (TME). Some of these aberrant functions include …
Emerging role of circular RNAs in hepatocellular carcinoma immunotherapy
Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …
The mechanism underlying the ncRNA dysregulation pattern in hepatocellular carcinoma and its tumor microenvironment
C Xue, X Gu, Z Bao, Y Su, J Lu, L Li - Frontiers in immunology, 2022 - frontiersin.org
HCC is one of the most common malignant tumors and has an extremely poor prognosis.
Accumulating studies have shown that noncoding RNA (ncRNA) plays an important role in …
Accumulating studies have shown that noncoding RNA (ncRNA) plays an important role in …
MALAT-1/p53/miR-155/miR-146a ceRNA circuit tuned by methoxylated quercitin glycoside alters immunogenic and oncogenic profiles of breast cancer
M Abdel-Latif, A Riad, RA Soliman, AM Elkhouly… - Molecular and Cellular …, 2022 - Springer
Abstract Triple-Negative Breast Cancer (TNBC) is one of the most aggressive and hot BC
subtypes. Our research group has recently shed the light on the utility of natural compounds …
subtypes. Our research group has recently shed the light on the utility of natural compounds …
[HTML][HTML] Long non-coding RNAs: functional regulatory players in breast cancer
RA Youness, MZ Gad - Non-coding RNA research, 2019 - Elsevier
Historically, the long-held protein-centered bias has denoted 98% of the human genome as
'Junk'DNA. However, the current work has shifted the perception of such'junk'transcriptional …
'Junk'DNA. However, the current work has shifted the perception of such'junk'transcriptional …
High mobility group box 1 in human cancer
High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
[HTML][HTML] Recent progress in the immunotherapy of hepatocellular carcinoma: Non-coding RNA-based immunotherapy may improve the outcome
Hepatocellular carcinoma (HCC) is the second most lethal cancer and a leading cause of
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …
cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) significantly …
[HTML][HTML] Targeting hydrogen sulphide signaling in breast cancer
Abstract Introduction Hydrogen sulphide (H 2 S) has been established as a key member of
the gasotransmitters family that recently showed a pivotal role in various pathological …
the gasotransmitters family that recently showed a pivotal role in various pathological …