Post-translational arginine methylation is responsible for regulation of many biological
processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1 …

Post-translational modifications (PTMs) of histone proteins are a hallmark of epigenetic
regulation. They provide a mechanism to modulate chromatin structure and constitute the …

Abstract Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse
cellular processes, including tumorigenesis, and its overexpression is observed in cell lines …

Homozygous deletions of p16/CDKN2A are prevalent in cancer, and these mutations
commonly involve co-deletion of adjacent genes, including methylthioadenosine …

Protein arginine methyltransferases (PRMTs) play important roles in several cellular
processes, including signaling, gene regulation, and transport of proteins and nucleic acids …

Protein arginine methyltransferases (PRMTs) catalyze arginine methylation on both
chromatin-bound and cytoplasmic proteins. Accumulating evidence supports the …

Full-length human protein arginine methyltransferase 7 (PRMT7) expressed as a fusion
protein in Escherichia coli was initially found to generate only ω-N G-monomethylated …

Many key cellular processes can be regulated by the seemingly simple addition of one, or
two, methyl groups to arginine residues by the nine known mammalian protein arginine …

Imatinib-insensitive leukemia stem cells (LSCs) are believed to be responsible for resistance
to BCR-ABL tyrosine kinase inhibitors and relapse of chronic myelogenous leukemia (CML) …

Arginine methylation is a common posttranslational modification (PTM) that alters roughly
0.5% of all arginine residues in the cells. There are three types of arginine methylation …