Addressing the challenges of split liver transplantation through technical advances. A systematic review

NS Lau, A Jacques, G McCaughan, M Crawford… - Transplantation …, 2021 - Elsevier
Background Split liver transplantation addresses donor shortages by facilitating the
transplant of two recipients using one donor liver. Some still consider these grafts inferior …

[HTML][HTML] British Transplantation Society guidelines on abdominal organ transplantation from deceased donors after circulatory death

B Phillips, E Asgari, M Berry, C Callaghan… - Transplantation …, 2023 - Elsevier
Abstract The British Transplantation Society (BTS)'Guideline on transplantation from
deceased donors after circulatory death'has recently been updated and this manuscript …

Ex situ dual hypothermic oxygenated machine perfusion for human split liver transplantation

AM Thorne, V Lantinga, S Bodewes… - Transplantation …, 2021 - journals.lww.com
Background. Liver splitting allows the opportunity to share a deceased graft between 2
recipients but remains underutilized. We hypothesized that liver splitting during continuous …

[HTML][HTML] Liver splitting during normothermic machine perfusion: a novel method to combine the advantages of both in-situ and ex-vivo techniques

NS Lau, M Ly, C Dennis, K Ewenson, H Ly, JL Huang… - HPB, 2023 - Elsevier
Background Split liver transplantation permits the transplant of two recipients using a single
donor liver. Liver splitting can be performed using the ex-vivo technique (more convenient) …

The new horizon of split‐liver transplantation: ex situ liver splitting during hypothermic oxygenated machine perfusion

M Spada, R Angelico, C Grimaldi… - Liver …, 2020 - Wiley Online Library
Split-liver grafts are more vulnerable to ischemia/reperfusion injury (IRI) and primary
nonfunction (PNF) because of prolonged cold ischemia time (CIT) and surgical …

Ex vivo liver splitting and hypothermic oxygenated machine perfusion: technical refinements of a promising preservation strategy in split liver transplantation

JY Mabrut, M Lesurtel, X Muller, R Dubois… - …, 2021 - journals.lww.com
J.-YM designed the research, performed the research, and wrote the article. ML and GR
performed the research and participated in writing the article. XM and RD participated in …

Prolonged ex vivo normothermic perfusion of a split liver: an innovative approach to increase the number of available grafts

NS Lau, M Ly, A Jacques, K Ewenson… - Transplantation …, 2021 - journals.lww.com
Normothermic machine perfusion has emerged as a method of assessing livers before
implantation and permits livers to be split ex vivo while perfused under normothermic …

Split-liver ex situ machine perfusion: a novel technique for studying organ preservation and therapeutic interventions

V Huang, N Karimian, D Detelich, S Raigani… - Journal of clinical …, 2020 - mdpi.com
Ex situ machine perfusion is a promising technology to help improve organ viability prior to
transplantation. However, preclinical studies using discarded human livers to evaluate …

Efficiency of machine perfusion in pediatric liver transplantation

A Parente, M Kasahara, VE De Meijer… - Liver …, 2024 - journals.lww.com
Liver transplantation is the only lifesaving procedure for children with end-stage liver
disease. The field is however heterogenic with various graft types, recipient age and weight …

Proof of concept: liver splitting during normothermic machine perfusion

BTF Stephenson, GK Bonney, RW Laing… - Journal of surgical …, 2018 - academic.oup.com
Introduction Despite utilizing extended criteria donors, there remains a shortage of livers for
transplantation. No data exists on splitting donor livers with concurrent NMP-L. Methods A …