[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant (B. 1.1. 529) has multiple spike protein
mutations, that contribute to viral escape from antibody neutralization,,–and reduce vaccine …

[HTML][HTML] SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron

A Tarke, CH Coelho, Z Zhang, JM Dan, ED Yu… - Cell, 2022 - cell.com
We address whether T cell responses induced by different vaccine platforms (mRNA-1273,
BNT162b2, Ad26. COV2. S, and NVX-CoV2373) cross-recognize early SARS-CoV-2 …

COVID-19 vaccination: The road ahead

DM Altmann, RJ Boyton - Science, 2022 - science.org
A diverse array of successful, first-generation SARS-CoV-2 vaccines have played a huge
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …

Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?

SJ Kent, DS Khoury, A Reynaldi, JA Juno… - Nature Reviews …, 2022 - nature.com
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines

G McLean, J Kamil, B Lee, P Moore, TF Schulz, A Muik… - MBio, 2022 - Am Soc Microbiol
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …

SARS-CoV-2 omicron variant: epidemiological features, biological characteristics, and clinical significance

Y Guo, J Han, Y Zhang, J He, W Yu, X Zhang… - Frontiers in …, 2022 - frontiersin.org
The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

An early warning system for emerging SARS-CoV-2 variants

L Subissi, A von Gottberg, L Thukral, N Worp… - Nature medicine, 2022 - nature.com
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Prior infection with SARS-CoV-2 boosts and broadens Ad26. COV2. S immunogenicity in a variant-dependent manner

R Keeton, SI Richardson, T Moyo-Gwete, T Hermanus… - Cell host & …, 2021 - cell.com
Summary The Johnson and Johnson Ad26. COV2. S single-dose vaccine represents an
attractive option for coronavirus disease 2019 (COVID-19) vaccination in countries with …