Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
The glycosylation in SARS-CoV-2 and its receptor ACE2
Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3
Great advances have been made in mass spectrometric data interpretation for intact
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
Optimal Dissociation Methods Differ for N- and O-Glycopeptides
NM Riley, SA Malaker, MD Driessen… - Journal of proteome …, 2020 - ACS Publications
Site-specific characterization of glycosylation requires intact glycopeptide analysis, and
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …
pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification
The precise and large-scale identification of intact glycopeptides is a critical step in
glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput …
glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput …
Glyco-Decipher enables glycan database-independent peptide matching and in-depth characterization of site-specific N-glycosylation
Z Fang, H Qin, J Mao, Z Wang, N Zhang… - Nature …, 2022 - nature.com
Glycopeptides with unusual glycans or poor peptide backbone fragmentation in tandem
mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and …
mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and …
Recent advances in computational algorithms and software for large-scale glycoproteomics
DA Polasky, AI Nesvizhskii - Current Opinion in Chemical Biology, 2023 - Elsevier
Glycoproteomics, or characterizing glycosylation events at a proteome scale, has seen rapid
advances in methods for analyzing glycopeptides by tandem mass spectrometry in recent …
advances in methods for analyzing glycopeptides by tandem mass spectrometry in recent …
Maturing glycoproteomics technologies provide unique structural insights into the N-glycoproteome and its regulation in health and disease
The glycoproteome remains severely understudied because of significant analytical
challenges associated with glycoproteomics, the system-wide analysis of intact …
challenges associated with glycoproteomics, the system-wide analysis of intact …
MS‐based glycomics and glycoproteomics methods enabling isomeric characterization
Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …