[HTML][HTML] ABCA1 and ABCG1 as potential therapeutic targets for the prevention of atherosclerosis

M Matsuo - Journal of pharmacological sciences, 2022 - Elsevier
Prevention of atherosclerosis is important because it is a risk factor for cardiovascular
diseases globally. One of the causes of atherosclerosis is accumulation of cholesterol and …

Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein: from mechanistic studies to clinical trials for COVID-19

J Huang, W Song, H Huang, Q Sun - Journal of clinical medicine, 2020 - mdpi.com
An outbreak of novel coronavirus-related pneumonia COVID-19, that was identified in
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Transendothelial transport of lipoproteins

E Jang, J Robert, L Rohrer, A von Eckardstein, WL Lee - Atherosclerosis, 2020 - Elsevier
The accumulation of low-density lipoproteins (LDL) in the arterial wall plays a pivotal role in
the initiation and pathogenesis of atherosclerosis. Conversely, the removal of cholesterol …

Role of resolvins in the inflammatory resolution of neurological diseases

C Li, X Wu, S Liu, D Shen, J Zhu, K Liu - Frontiers in pharmacology, 2020 - frontiersin.org
The occurrence of neurological diseases including neurodegenerative disorders,
neuroimmune diseases, and cerebrovascular disorders is closely related to …

Cardiovascular protective effect of black pepper (Piper nigrum L.) and its major bioactive constituent piperine

D Wang, L Zhang, J Huang, K Himabindu… - Trends in Food Science …, 2021 - Elsevier
Abstract Background Cardiovascular diseases (CVDs) are the leading cause of death
worldwide. Black pepper, the fruits of Piper nigrum L., is well known as “the king of spices” …

Alterations of HDL's to piHDL's proteome in patients with chronic inflammatory diseases, and HDL-targeted therapies

V Vyletelová, M Nováková, Ľ Pašková - Pharmaceuticals, 2022 - mdpi.com
Chronic inflammatory diseases, such as rheumatoid arthritis, steatohepatitis, periodontitis,
chronic kidney disease, and others are associated with an increased risk of atherosclerotic …

Clinical pharmacokinetics and pharmacodynamics of CSL112

L Ortega-Paz, S Giordano, D Capodanno… - Clinical …, 2023 - Springer
Cardiovascular diseases are the leading cause of death worldwide. Although there have
been substantial advances over the last decades, recurrent adverse cardiovascular events …

Scavenging reactive lipids to prevent oxidative injury

LS May-Zhang, A Kirabo, J Huang… - Annual Review of …, 2021 - annualreviews.org
Oxidative injury due to elevated levels of reactive oxygen species is implicated in
cardiovascular diseases, Alzheimer's disease, lung and liver diseases, and many cancers …

High density lipoprotein in atherosclerosis and coronary heart disease: where do we stand today?

E Zvintzou, DS Karampela, A Vakka, E Xepapadaki… - Vascular …, 2021 - Elsevier
Epidemiological studies during the last five years suggest that a relation between high
density lipoprotein cholesterol (HDL-C) levels and the risk for cardiovascular disease (CVD) …