While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …

Translational research has revolutionized how we develop new treatments for cancer
patients. The change from an organ-centric concept guiding treatment choice towards deep …

Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

Metabolic reprogramming is one of the hallmarks of tumors. Alterations of cellular
metabolism not only contribute to tumor development, but also mediate the resistance of …

Metabolomics plays a pivotal role in systems biology, and NMR is a central tool with high
precision and exceptional resolution of chemical information. Most NMR metabolomic …

Metabolomics encompasses the systematic identification and quantification of all metabolic
products in the human body. This field could provide clinicians with novel sets of diagnostic …

Although colorectal cancer (CRC) is considered one of the most preventable cancers, no
non-invasive, accurate diagnostic tool to screen CRC exists. We explored the potential of …

Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted
extraordinary progress in Organ-on-Chip (OoC) technology, leading to the development of in …

Hyperpolarized nuclear magnetic resonance (NMR) offers an ensemble of methods that
remarkably address the sensitivity issues of conventional NMR. Dissolution Dynamic …

Metabolism is the collection of biochemical reactions enabled by chemically diverse
metabolites, which facilitate different physiological processes to exchange substances and …