Diet and Nutraceuticals for treatment and prevention of primary and secondary stroke: emphasis on nutritional antiplatelet and antithrombotic agents

R Kakarla, LA Vinjavarapu, S Krishnamurthy - Neurochemistry International, 2024 - Elsevier
Ischemic stroke is a devastating disease that causes morbidity and mortality. Malnutrition
following ischemic stroke is common in stroke patients. During the rehabilitation, the death …

Platelet storage: Progress so far

V Rajashekaraiah, MC Rajanand - Journal of Thrombosis and …, 2023 - Springer
There is a crucial need for platelet transfusion during an emergency—surgery and treatment
of platelet disorders. The unavailability of donors has furthermore increased the demand for …

Liposomal Resveratrol Alleviates Platelet Storage Lesion via Antioxidation and the Physical Buffering Effect

J Hou, W Xiong, X Shao, L Long, Y Chang… - … Applied Materials & …, 2023 - ACS Publications
Platelet transfusion is essential in the treatment of platelet-related diseases and the
prevention of bleeding in patients with surgical procedures. Platelet transfusion efficacy and …

Dietary l-carnitine affects leukocyte count and function in dairy cows around parturition

SU Kononov, J Meyer, J Frahm, S Kersten… - Frontiers in …, 2022 - frontiersin.org
In early lactation, an energy deficit leading to a negative energy balance (NEB) is associated
with increased susceptibility to disease and has been shown to be an important factor during …

Long-term cold storage of platelets for transfusion based on zwitterionic magnetic microgels

Y Fu, Y Ma, Y Tian, L Zhang, J Yang, L Zhang - Chemical Engineering …, 2024 - Elsevier
Hypothermic preservation of platelets at 22° C with an agitation process realizes their rapid
transfusion to treat hemorrhage and thrombocytopenia in the clinic. However, platelets suffer …

[HTML][HTML] Utilization of mitochondrial-targeted small molecules in protecting stored platelets against storage lesions

Y Zhang, J Wang, S Lei, Y Hu, L Fu - European Journal of Medicinal …, 2022 - Elsevier
Platelet transfusion is frequently applied to control and prevent bleeding under many clinical
settings. However, the current storage strategy limits the collected platelets to a shelf life of …

Resveratrol reduces platelet storage lesion by preventing free mitochondrial DNA (mtDNA) accumulation in platelet concentrates during storage

K Haeri, S Samiee, S Hajati, M Deyhim - Journal of Thrombosis and …, 2023 - Springer
Platelet activation and mitochondrial damage are among the crucial events leading to the
quality reduction of platelet concentrates (PCs) during preparation and storage, called …

l-carnitine modulates free mitochondrial DNA DAMPs and platelet storage lesions during storage of platelet concentrates

S Bagheri, S Samiee, MN Zarif, MR Deyhim - Journal of Thrombosis and …, 2023 - Springer
Platelet storage lesions may occur in Platelet concentrates (PCs) storage time, reducing
PCs' quality. Mitochondrial damage causes mitochondrial DNA (mtDNA) to be released into …

Nanomedicine‐mediated recovery of antioxidant glutathione peroxidase activity after oxidative‐stress cellular damage: Insights for neurological long COVID

T Akanchise, B Angelov… - Journal of Medical …, 2024 - Wiley Online Library
Nanomedicine for treating post‐viral infectious disease syndrome is at an emerging stage.
Despite promising results from preclinical studies on conventional antioxidants, their clinical …

Effects of L-carnitine supplementation in patients with childhood-onset epilepsy prescribed valproate

A Okumura, M Takagi, S Numoto, H Iwayama… - Epilepsy & Behavior, 2021 - Elsevier
Background The benefits of carnitine supplementation in patients treated with valproate
(VPA) are not clear. Therefore, we retrospectively explored the benefits of carnitine …