Epidemiology of heart failure
A Groenewegen, FH Rutten, A Mosterd… - European journal of …, 2020 - Wiley Online Library
The heart failure syndrome has first been described as an emerging epidemic about 25
years ago. Today, because of a growing and ageing population, the total number of heart …
years ago. Today, because of a growing and ageing population, the total number of heart …
Reappraising the role of inflammation in heart failure
The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …
circulating levels of pro-inflammatory cytokines opened a new area of research that has …
Systemic immune‐inflammation index (SII) predicted clinical outcome in patients with coronary artery disease
Background This study examines the predictive value of a novel systemic immune‐
inflammation index (SII, platelet× neutrophil/lymphocyte ratio) in coronary artery disease …
inflammation index (SII, platelet× neutrophil/lymphocyte ratio) in coronary artery disease …
Mechanisms of cardiovascular benefits of sodium glucose co-transporter 2 (SGLT2) inhibitors: a state-of-the-art review
GD Lopaschuk, S Verma - Basic to Translational Science, 2020 - jacc.org
Recent clinical trials have shown that sodium glucose co-transport 2 (SGLT2) inhibitors have
dramatic beneficial cardiovascular outcomes. These include a reduced incidence of …
dramatic beneficial cardiovascular outcomes. These include a reduced incidence of …
Inflammatory cytokines and chemokines as therapeutic targets in heart failure
A Hanna, NG Frangogiannis - Cardiovascular Drugs and Therapy, 2020 - Springer
Heart failure exhibits remarkable pathophysiologic heterogeneity. A large body of evidence
suggests that regardless of the underlying etiology, heart failure is associated with induction …
suggests that regardless of the underlying etiology, heart failure is associated with induction …
Heart failure in type 2 diabetes mellitus: impact of glucose-lowering agents, heart failure therapies, and novel therapeutic strategies
HC Kenny, ED Abel - Circulation research, 2019 - Am Heart Assoc
Patients with diabetes mellitus have> 2× the risk for developing heart failure (HF; HF with
reduced ejection fraction and HF with preserved ejection fraction). Cardiovascular …
reduced ejection fraction and HF with preserved ejection fraction). Cardiovascular …
Resident cardiac macrophages: Heterogeneity and function in health and disease
R Zaman, S Epelman - Immunity, 2022 - cell.com
Understanding tissue macrophage biology has become challenging in recent years due the
ever-increasing complexity in macrophage-subset identification and functional …
ever-increasing complexity in macrophage-subset identification and functional …
Dietary metabolism, the gut microbiome, and heart failure
Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …
diseases have expanded our insight into how microbial composition and function affect the …
Obesity, hypertension, and cardiac dysfunction: novel roles of immunometabolism in macrophage activation and inflammation
AJ Mouton, X Li, ME Hall, JE Hall - Circulation research, 2020 - Am Heart Assoc
Obesity and hypertension, which often coexist, are major risk factors for heart failure and are
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …
Coronavirus disease 2019 hospitalizations attributable to cardiometabolic conditions in the United States: a comparative risk assessment analysis
BACKGROUND Risk of coronavirus disease 2019 (COVID‐19) hospitalization is robustly
linked to cardiometabolic health. We estimated the absolute and proportional COVID‐19 …
linked to cardiometabolic health. We estimated the absolute and proportional COVID‐19 …