N6-Methyladenosine mRNA Modification: From Modification Site Selectivity to Neurological Functions

Z Zhang, XJ Wang - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus The development of various chemical methods has enabled scientists to
decipher the distribution features and biological functions of RNA modifications in the past …

[HTML][HTML] Cohesin regulation and roles in chromosome structure and function

NL Rittenhouse, JM Dowen - Current Opinion in Genetics & Development, 2024 - Elsevier
Chromosome structure regulates DNA-templated processes such as transcription of genes.
Dynamic changes to chromosome structure occur during development and in disease …

Ionizing radiation induces vascular smooth muscle cell senescence through activating NF-κB/CTCF/p16 pathway

X Zheng, Z Liu, Y Bin, J Wang, X Rao, G Wu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Radiation injury of blood vessels (RIBV) is a serious long-term complication of radiotherapy,
characterized by the development of atherosclerosis. The involvement of vascular smooth …

LncRNA CARMN inhibits abdominal aortic aneurysm formation and vascular smooth muscle cell phenotypic transformation by interacting with SRF

S Liu, H Zhou, D Han, H Song, Y Li, S He, Y Du… - Cellular and Molecular …, 2024 - Springer
Phenotypic transformation of vascular smooth muscle cells (VSMCs) plays a crucial role in
abdominal aortic aneurysm (AAA) formation. CARMN, a highly conserved, VSMC-enriched …

The chromatin conformation landscape of Alzheimer's disease

R Nativio, Y Lan, G Donahue, O Shcherbakova… - bioRxiv, 2024 - biorxiv.org
We have been investigating epigenetic alterations in the brain during human aging and
Alzheimer's disease (AD), and have evidence for histone acetylation both protecting the …

Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis

J Cossmann, PI Kos, V Varamogianni-Mamatsi… - bioRxiv, 2023 - biorxiv.org
The three-dimensional folding of chromosomes is essential for nuclear functions such as
DNA replication and gene regulation. The emergence of chromatin architecture is thus an …