[HTML][HTML] The evolving role of investigative toxicology in the pharmaceutical industry
F Pognan, M Beilmann, H Boonen, A Czich… - Nature reviews drug …, 2023 - nature.com
For decades, preclinical toxicology was essentially a descriptive discipline in which
treatment-related effects were carefully reported and used as a basis to calculate safety …
treatment-related effects were carefully reported and used as a basis to calculate safety …
Applications of multi-omics technologies for crop improvement
Y Yang, MA Saand, L Huang, WB Abdelaal… - Frontiers in Plant …, 2021 - frontiersin.org
Multiple “omics” approaches have emerged as successful technologies for plant systems
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …
Breeding and genomic approaches towards development of fusarium wilt resistance in chickpea
Chickpea is an important leguminous crop with potential to provide dietary proteins to both
humans and animals. It also ameliorates soil nitrogen through biological nitrogen fixation …
humans and animals. It also ameliorates soil nitrogen through biological nitrogen fixation …
Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts
SA Goutman, K Guo, MG Savelieff, A Patterson… - Brain, 2022 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease lacking effective
treatments. This is due, in part, to a complex and incompletely understood pathophysiology …
treatments. This is due, in part, to a complex and incompletely understood pathophysiology …
A review of integrative omic approaches for understanding rice salt response mechanisms
Soil salinity is one of the most serious environmental challenges, posing a growing threat to
agriculture across the world. Soil salinity has a significant impact on rice growth …
agriculture across the world. Soil salinity has a significant impact on rice growth …
Metabolomic profile of diabetic retinopathy: a GC-TOFMS-based approach using vitreous and aqueous humor
H Wang, J Fang, F Chen, Q Sun, X Xu, SH Lin, K Liu - Acta diabetologica, 2020 - Springer
Aim To identify the potential metabolite markers in diabetic retinopathy (DR) by using gas
chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). Methods GC …
chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). Methods GC …
[HTML][HTML] Exploring the roles of microorganisms and metabolites in the 30-year aging process of the dried pericarps of Citrus reticulata'Chachi'based on high …
F Wang, Y Hu, H Chen, L Chen, Y Liu - Food Research International, 2023 - Elsevier
GuangChenpi (GCP), the dried pericarps of Citrus reticulata'Chachi', has been consumed
daily as a food and dietary supplement in China for centuries. Its health benefits are …
daily as a food and dietary supplement in China for centuries. Its health benefits are …
Metabolomic-based studies of the intake of virgin olive oil: a comprehensive review
A Vazquez-Aguilar, E Sanchez-Rodriguez… - Metabolites, 2023 - mdpi.com
Virgin olive oil (VOO) is a high-value product from the Mediterranean diet. Some health and
nutritional benefits have been associated with its consumption, not only because of its …
nutritional benefits have been associated with its consumption, not only because of its …
Blood metabolomics analysis identifies differential serum metabolites in elite and sub-elite swimmers
M Cai, C Wu, C Jing, X Shen, M He, L Wang… - Frontiers in …, 2022 - frontiersin.org
Objective: Metabolites in body fluids, such as lactate, glucose, and creatinine, have been
measured by conventional methods to evaluate physical function and performance or …
measured by conventional methods to evaluate physical function and performance or …
Transcriptome and metabolome profiling of interspecific CSSLs reveals general and specific mechanisms of drought resistance in cotton
B Han, F Wang, Z Liu, L Chen, D Yue, W Sun… - Theoretical and Applied …, 2022 - Springer
In order to understand the molecular mechanism of cotton's response to drought during the
flowering and boll stage, transcriptomics and metabolomics were carried out for two …
flowering and boll stage, transcriptomics and metabolomics were carried out for two …