Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis

JS Zifodya, JS Kreniske, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …

Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement

J Domínguez, EC Boettger, D Cirillo… - … of tuberculosis and …, 2016 - ingentaconnect.com
The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as …

Comparison of Xpert MTB/RIF assay and GenoType MTBDR plus DNA probes for detection of mutations associated with rifampicin resistance in Mycobacterium …

A Rahman, M Sahrin, S Afrin, K Earley, S Ahmed… - PloS one, 2016 - journals.plos.org
Background GeneXpert MTB/RIF (Xpert) and Genotype MTBDR plus (DR plus) are two
World Health Organization (WHO) endorsed probe based molecular drug susceptibility …

Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapy

A Trauner, S Borrell, K Reither, S Gagneux - Drugs, 2014 - Springer
Drug-resistant tuberculosis is a growing threat to global public health. Recent efforts to
understand the evolution of drug resistance have shown that changes in drug–target …

Development of new therapeutics to meet the current challenge of drug resistant tuberculosis

BA Sheikh, BA Bhat, U Mehraj, W Mir… - Current …, 2021 - ingentaconnect.com
Tuberculosis (TB) is a prominent infective disease and a major reason of mortality/morbidity
globally. Mycobacterium tuberculosis causes a long-lasting latent infection in a significant …

d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal

D Deshpande, JWC Alffenaar, CU Köser… - Clinical Infectious …, 2018 - academic.oup.com
Background d-cycloserine is used to treat multidrug-resistant tuberculosis. Its efficacy,
contribution in combination therapy, and best clinical dose are unclear, also data on the d …

Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might …

J Advani, R Verma, O Chatterjee, PK Pachouri… - Frontiers in …, 2019 - frontiersin.org
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been constructive in
understanding its evolution, genetic diversity and the mechanisms involved in drug …

Discordance across Phenotypic and Molecular Methods for Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates in a Low TB Incidence …

S Ahmad, E Mokaddas, N Al-Mutairi, HS Eldeen… - PLoS …, 2016 - journals.plos.org
With increasing incidence of multidrug-resistant tuberculosis (MDR-TB), accurate drug
susceptibility testing (DST) of Mycobacterium tuberculosis to first-line drugs has become …

Formulation and optimization of long acting dual niosomes using box-Behnken experimental design method for combinative delivery of ethionamide and D …

P Kulkarni, D Rawtani, T Barot - Colloids and Surfaces A: Physicochemical …, 2019 - Elsevier
The ability of niosomes to entrap both hydrophilic (D-Cycloserine) and lipophilic
(Ethionamide) drugs was utilized to make an effective formulation for combating drug …