Systematic reviews are characterized by a methodical and replicable methodology and
presentation. They involve a comprehensive search to locate all relevant published and …

Background The respiratory illness caused by SARS‐CoV‐2 infection continues to present
diagnostic challenges. Our 2020 edition of this review showed thoracic (chest) imaging to be …

In response to limitations in the understanding and use of published evidence, evidence-
based medicine (EBM) began as a movement in the early 1990s. EBM's initial focus was on …

BACKGROUND Initial observational studies and a systematic review published 5 years ago
have suggested that obstetric and perinatal outcomes are better in offspring conceived …

Psychology has recently been viewed as facing a replication crisis because efforts to
replicate past study findings frequently do not show the same result. Often, the first study …

No consensus exists regarding which are the most effective mechanisms to promote
household action on climate change. We present a meta-analysis of randomised controlled …

In this volume of the IJE, Gao and colleagues explore the causal effect of adiposity on
several cancers using twosample Mendelian randomization (MR), and find some evidence …

Background Coronary heart disease (CHD) is the most common cause of death globally.
However, with falling CHD mortality rates, an increasing number of people living with CHD …

High quality protocols facilitate proper conduct, reporting, and external review of clinical
trials. However, the completeness of trial protocols is often inadequate. To help improve the …

Meta‐analysis and meta‐regression are statistical methods for synthesizing and modelling
the results of different studies, and are critical research synthesis tools in ecology and …