Decoding the organization of spinal circuits that control locomotion
O Kiehn - Nature Reviews Neuroscience, 2016 - nature.com
Unravelling the functional operation of neuronal networks and linking cellular activity to
specific behavioural outcomes are among the biggest challenges in neuroscience. In this …
specific behavioural outcomes are among the biggest challenges in neuroscience. In this …
[HTML][HTML] Control of mammalian locomotion by somatosensory feedback
A Frigon, T Akay, BI Prilutsky - Comprehensive physiology, 2021 - ncbi.nlm.nih.gov
When animals walk overground, mechanical stimuli activate various receptors located in
muscles, joints and skin. Afferents from these mechanoreceptors project to neuronal …
muscles, joints and skin. Afferents from these mechanoreceptors project to neuronal …
Computational modeling of spinal circuits controlling limb coordination and gaits in quadrupeds
Interactions between cervical and lumbar spinal circuits are mediated by long propriospinal
neurons (LPNs). Ablation of descending LPNs in mice disturbs left-right coordination at high …
neurons (LPNs). Ablation of descending LPNs in mice disturbs left-right coordination at high …
Organization of the mammalian locomotor CPG: review of computational model and circuit architectures based on genetically identified spinal interneurons
IA Rybak, KJ Dougherty, NA Shevtsova - ENeuro, 2015 - eneuro.org
The organization of neural circuits that form the locomotor central pattern generator (CPG)
and provide flexor–extensor and left–right coordination of neuronal activity remains largely …
and provide flexor–extensor and left–right coordination of neuronal activity remains largely …
Central control of interlimb coordination and speed‐dependent gait expression in quadrupeds
Key points Quadrupeds express different gaits depending on speed of locomotion. Central
pattern generators (one per limb) within the spinal cord generate locomotor oscillations and …
pattern generators (one per limb) within the spinal cord generate locomotor oscillations and …
Sub-populations of spinal V3 interneurons form focal modules of layered pre-motor microcircuits
Layering of neural circuits facilitates the separation of neurons with high spatial sensitivity
from those that play integrative temporal roles. Although anatomical layers are readily …
from those that play integrative temporal roles. Although anatomical layers are readily …
State-dependent rhythmogenesis and frequency control in a half-center locomotor CPG
The spinal locomotor central pattern generator (CPG) generates rhythmic activity with
alternating flexion and extension phases. This rhythmic pattern is likely to result from …
alternating flexion and extension phases. This rhythmic pattern is likely to result from …
Computational modeling of brainstem circuits controlling locomotor frequency and gait
A series of recent studies identified key structures in the mesencephalic locomotor region
and the caudal brainstem of mice involved in the initiation and control of slow (exploratory) …
and the caudal brainstem of mice involved in the initiation and control of slow (exploratory) …
The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice
H Zhang, NA Shevtsova, D Deska-Gauthier, C Mackay… - Elife, 2022 - elifesciences.org
Speed-dependent interlimb coordination allows animals to maintain stable locomotion
under different circumstances. The V3 neurons are known to be involved in interlimb …
under different circumstances. The V3 neurons are known to be involved in interlimb …
Descending neurons coordinate anterior grooming behavior in Drosophila
L Guo, N Zhang, JH Simpson - Current Biology, 2022 - cell.com
The brain coordinates the movements that constitute behavior, but how descending neurons
convey the myriad of commands required to activate the motor neurons of the limbs in the …
convey the myriad of commands required to activate the motor neurons of the limbs in the …