Abstract Argentatins A–C (1–3), the major cycloartane-type triterpenoids of guayule resin, a
byproduct of commercial rubber production, were converted into their pyrimidine (7–12) …

Abstract Background and Purpose Postoperative pain occurs in as many as 70% of
surgeries performed worldwide. Postoperative pain management still relies on opioids …

The need for the discovery and development of new pharmaceuticals for the treatment of
cancer demands that all approaches to drug discovery should be exploited. Among the …

Approximately one-third of the waste biomass from the cultivation of guayule (Parthenium
argentatum A. Gray) for natural rubber production is leaf tissue; however, whether it can be …

The argentatins are the most abundant compounds in guayule resin with promising potential
for the biopharmaceutical industry. However, their accumulation along the vegetative cycle …

Parthenium argentatum (Gray), commonly known as guayule, has been used to obtain
natural rubber since the beginning of the 20th century. Additionally, the so called “resin” is a …

Argentatins are secondary metabolites synthesized by guayule (Parthenium argentatum A.
Gray) with numerous potential medical applications. In addition to inhibiting insect growth …

A series of acenaphtho [1, 2-b] pyrrole derivatives were synthesized and their intercalation
geometries with DNA and antitumor activities were investigated in detail. From combination …

There is considerable interest in the exploitation of compounds belonging to the triterpenoid
family from guayule (Parthenium argentatum, A. Gray), as they offer several beneficial effects …

Synthesis, characterization, anticancer activity, and comparative molecular field analysis
(CoMFA) of 14 argentatin B (1) analogs are described. The effect of argentatin B derivatives …