Non-union of bone following fracture is an orthopaedic condition with a high morbidity and
clinical burden. Despite its estimated global prevalence of nine million annually, the limit of …

Ferroelectric materials (FEMs), possessing piezoelectric, pyroelectric, inverse piezoelectric,
nonlinear optic, ferroelectric‐photovoltaic, and many other properties, are attracting …

Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter
its morphology and function in response to stimuli in its surrounding environment. The ability …

Bone grafts are one of the most commonly transplanted tissues. However, autologous grafts
are in short supply, and can be associated with pain and donor-site morbidity. The creation …

Stem cell fate can be directed through the application of various external physical stimuli,
enabling a controlled approach to targeted differentiation. Studies involving the use of …

In the past decades, bone tissue engineering developed and exploited many typologies of
bioreactors, which, besides providing proper culture conditions, aimed at integrating those …

Adult or mesenchymal stem cells (MSCs) have been found in different tissues in the body,
residing in stem cell microenvironments called “stem cell niches”. They play different roles …

Mechanical signals are ubiquitous in our everyday life and the process of converting these
mechanical signals into a biological signalling response is known as mechanotransduction …

Bone marrow mesenchymal stem cells that are committed to adipogenesis were exposed
daily to high-frequency low-intensity mechanical vibrations to understand molecular …

The ability to control cell behaviour, cell fate and simulate reliable tissue models in vitro
remains a significant challenge yet is crucial for various applications of high throughput …