Pathogenesis and virulence of herpes simplex virus

S Zhu, A Viejo-Borbolla - Virulence, 2021 - Taylor & Francis
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

[HTML][HTML] Herpesvirus latency

JI Cohen - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

[HTML][HTML] Herpes simplex virus type 1 infection of the central nervous system: insights into proposed interrelationships with neurodegenerative disorders

LF Duarte, MA Farías, DM Álvarez… - Frontiers in Cellular …, 2019 - frontiersin.org
Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can reach the brain
without evident clinical symptoms. Once in the central nervous system (CNS), the virus can …

The molecular basis of herpes simplex virus latency

MP Nicoll, JT Proença… - FEMS microbiology …, 2012 - academic.oup.com
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

Herpes Simplex Virus Type 1 infection: overview on relevant clinico‐pathological features

PG Arduino, SR Porter - Journal of oral pathology & medicine, 2008 - Wiley Online Library
Herpes Simplex Virus Type 1 (HSV‐1) is a nuclear replicating enveloped virus, usually
acquired through direct contact with infected lesions or body fluids (typically saliva). The …

Latency and reactivation of human cytomegalovirus

J Sinclair, P Sissons - Journal of General Virology, 2006 - microbiologyresearch.org
Human cytomegalovirus (HCMV) persists as a subclinical, lifelong infection in the normal
human host, maintained at least in part by its carriage in the absence of detectable infectious …

Chromatin control of herpes simplex virus lytic and latent infection

DM Knipe, A Cliffe - Nature reviews microbiology, 2008 - nature.com
Herpes simplex viruses (HSV) can undergo a lytic infection in epithelial cells and a latent
infection in sensory neurons. During latency the virus persists until reactivation, which leads …

Herpes simplex keratitis

S Kaye, A Choudhary - Progress in retinal and eye research, 2006 - Elsevier
Herpes simplex keratitis (HSK) results from an infection with the herpes simplex virus type 1
(HSV-1) also known as human herpesvirus type 1 (HHV-1). Primary infection may involve an …

An inquiry into the molecular basis of HSV latency and reactivation

B Roizman, RJ Whitley - Annual review of microbiology, 2013 - annualreviews.org
Herpes simplex virus (HSV) evolved an elegant strategy that enables the virus to impact a
large fraction of the human population. The virus replicates at the portal of entry (mouth …

A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation

PGE Kennedy, J Rovnak… - Journal of General …, 2015 - microbiologyresearch.org
Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV;
human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong …