Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …
Porcupine-inspired microneedles coupled with an adhesive back patching as dressing for accelerating diabetic wound healing
Diabetes chronic wound is a severe and frequently occurring medical issue in patients with
diabetes that often leads to more serious complications. Microneedles (MNs) can be used …
diabetes that often leads to more serious complications. Microneedles (MNs) can be used …
Microneedle-mediated transdermal delivery of biopharmaceuticals
HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …
administration. However, this strategy is generally limited to a few molecules with specific …
Advanced multifunctional nano-lipid carrier loaded gel for targeted delivery of 5-flurouracil and cannabidiol against non-melanoma skin cancer
Non-melanoma skin cancer is one of the most common malignancies reported around the
globe. Current treatment therapies fail to meet the desired therapeutic efficacy due to high …
globe. Current treatment therapies fail to meet the desired therapeutic efficacy due to high …
Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
Exploring the remarkable chemotherapeutic potential of polyphenolic antioxidants in battling various forms of cancer
M Imran, A Insaf, N Hasan, VV Sugandhi, D Shrestha… - Molecules, 2023 - mdpi.com
Plant-derived compounds, specifically antioxidants, have played an important role in
scavenging the free radicals present under diseased conditions. The persistent generation …
scavenging the free radicals present under diseased conditions. The persistent generation …
Advanced targeted drug delivery by bioengineered white blood cell-membrane camouflaged nanoparticulate delivery nanostructures
Targeted drug delivery has emerged as a pivotal approach within precision medicine,
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Leukocyte …
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Leukocyte …
Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract
S Zhang, C Zhu, W Huang, H Liu, M Yang… - Journal of Controlled …, 2023 - Elsevier
Oral administration is a convenient administration route for gastrointestinal disease therapy
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …
A temperature-responsive dual-hormone foam nanoengine improves rectal absorptivity of insulin-pramlintide for diabetes treatment
S Feng, Y Zhang, C Hou, Y Liu, Y Gao, Y Song… - Science …, 2024 - science.org
Despite the therapeutic benefits of insulin-pramlintide dual-hormone therapy in diabetes, its
application potential has been limited due to a lack of efficient delivery routes. Here, we …
application potential has been limited due to a lack of efficient delivery routes. Here, we …