Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches

N Hasan, A Nadaf, M Imran, U Jiba, A Sheikh… - Molecular cancer, 2023 - Springer
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …

Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery

M Hu, X Li, Z You, R Cai, C Chen - Advanced Materials, 2024 - Wiley Online Library
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Porcupine-inspired microneedles coupled with an adhesive back patching as dressing for accelerating diabetic wound healing

T Liu, Y Sun, G Jiang, W Zhang, R Wang, L Nie… - Acta Biomaterialia, 2023 - Elsevier
Diabetes chronic wound is a severe and frequently occurring medical issue in patients with
diabetes that often leads to more serious complications. Microneedles (MNs) can be used …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Advanced multifunctional nano-lipid carrier loaded gel for targeted delivery of 5-flurouracil and cannabidiol against non-melanoma skin cancer

N Hasan, M Imran, A Sheikh, N Tiwari, A Jaimini… - Environmental …, 2023 - Elsevier
Non-melanoma skin cancer is one of the most common malignancies reported around the
globe. Current treatment therapies fail to meet the desired therapeutic efficacy due to high …

Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration

GTY Yau, W Tai, JC Arnold, HK Chan… - Pharmaceutical …, 2023 - Springer
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …

Exploring the remarkable chemotherapeutic potential of polyphenolic antioxidants in battling various forms of cancer

M Imran, A Insaf, N Hasan, VV Sugandhi, D Shrestha… - Molecules, 2023 - mdpi.com
Plant-derived compounds, specifically antioxidants, have played an important role in
scavenging the free radicals present under diseased conditions. The persistent generation …

Advanced targeted drug delivery by bioengineered white blood cell-membrane camouflaged nanoparticulate delivery nanostructures

N Hasan, M Imran, D Jain, SK Jha, A Nadaf… - Environmental …, 2023 - Elsevier
Targeted drug delivery has emerged as a pivotal approach within precision medicine,
aiming to optimize therapeutic efficacy while minimizing systemic side effects. Leukocyte …

Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract

S Zhang, C Zhu, W Huang, H Liu, M Yang… - Journal of Controlled …, 2023 - Elsevier
Oral administration is a convenient administration route for gastrointestinal disease therapy
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …

A temperature-responsive dual-hormone foam nanoengine improves rectal absorptivity of insulin-pramlintide for diabetes treatment

S Feng, Y Zhang, C Hou, Y Liu, Y Gao, Y Song… - Science …, 2024 - science.org
Despite the therapeutic benefits of insulin-pramlintide dual-hormone therapy in diabetes, its
application potential has been limited due to a lack of efficient delivery routes. Here, we …