The synergistic effects of curcumin and chemotherapeutic drugs in inhibiting metastatic, invasive and proliferative pathways
M Younes, R Mardirossian, L Rizk, T Fazlian… - Plants, 2022 - mdpi.com
Curcumin, the main phytochemical identified from the Curcuma longa L. family, is one of the
spices used in alternative medicine worldwide. It has exhibited a broad range of …
spices used in alternative medicine worldwide. It has exhibited a broad range of …
[HTML][HTML] Resveratrol and p53: How are they involved in CRC plasticity and apoptosis?
A Brockmueller, C Buhrmann… - Journal of Advanced …, 2024 - Elsevier
Background Colorectal cancer (CRC), which is mainly caused by epigenetic and lifestyle
factors, is very often associated with functional plasticity during its development. In addition …
factors, is very often associated with functional plasticity during its development. In addition …
[HTML][HTML] Investigating the physicochemical properties and pharmacokinetics of curcumin employing density functional theory and gastric protection
The extraction, isolation as well as theoretical investigation of Cumcuma Xanthoriz (cxz)
molecule was evaluated to ascertain the physicochemical properties (pc) of the investigated …
molecule was evaluated to ascertain the physicochemical properties (pc) of the investigated …
Novel nano-sized metal complexes based on aceclofenac and glycine ligands: Synthesis, Characterization, molecular docking studies and their enhanced efficacy in …
New nano metal complexes of Cu (II), Zr (IV), La (III), Th (IV) and U (VI) ions using Acecl as
primary ligand and glycine (Gly) as secondary ligand were synthesized and characterized …
primary ligand and glycine (Gly) as secondary ligand were synthesized and characterized …
Synthesis and chemopreventive potential of 5-fu/genistein hybrids on colorectal cancer cells
G Moreno-Quintero, W Castrillón-Lopez… - Pharmaceuticals, 2022 - mdpi.com
A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by
spectroscopic analysis. The chemopreventive potential of these compounds was evaluated …
spectroscopic analysis. The chemopreventive potential of these compounds was evaluated …
Unraveling cancer progression pathways and phytochemical therapeutic strategies for its management
Cancer prevention is currently envisioned as a molecular-based approach to prevent
carcinogenesis in pre-cancerous stages, ie, dysplasia and carcinoma in situ. Cancer is the …
carcinogenesis in pre-cancerous stages, ie, dysplasia and carcinoma in situ. Cancer is the …
New Hybrid Scaffolds Based on 5-FU/Curcumin: Synthesis, Cytotoxic, Antiproliferative and Pro-Apoptotic Effect
G Moreno-Quintero, E Betancur-Zapata… - Pharmaceutics, 2023 - mdpi.com
A series of 5-FU-Curcumin hybrids were synthesized, and their structures were elucidated
by spectroscopic analysis. The synthesized hybrid compounds were evaluated in different …
by spectroscopic analysis. The synthesized hybrid compounds were evaluated in different …
[HTML][HTML] Validity and value of metabolic connectivity in mouse models of β-amyloid and tauopathy
F Ruch, J Gnörich, K Wind, M Köhler, A Zatcepin… - NeuroImage, 2024 - Elsevier
Among functional imaging methods, metabolic connectivity (MC) is increasingly used for
investigation of regional network changes to examine the pathophysiology of …
investigation of regional network changes to examine the pathophysiology of …
Resveratrol/Hydrazone hybrids: Synthesis and Chemopreventive activity against colorectal cancer cells
W Castrillón-López, A Herrera-Ramírez… - Pharmaceutics, 2022 - mdpi.com
A series of resveratrol/hydrazone hybrids were obtained and elucidated by spectroscopic
analysis. All compounds were evaluated against colorectal cancer cells (SW480 and …
analysis. All compounds were evaluated against colorectal cancer cells (SW480 and …
Corn Silk Alleviates Paclitaxel–Induced Lung Toxicity in Rats.
AI Barakat, SH El-Nabi… - Journal of Medical and Life …, 2024 - journals.ekb.eg
Background: Corn silk is a yellow, silky substance that arises from the stigma of a female
flower at the tip of the corn cob in the maize plant. The chemotherapeutic drug paclitaxel …
flower at the tip of the corn cob in the maize plant. The chemotherapeutic drug paclitaxel …