The critical role of RNA processing and degradation in the control of gene expression

CM Arraiano, JM Andrade, S Domingues… - FEMS microbiology …, 2010 - academic.oup.com
The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

Post-transcriptional gene regulation: from genome-wide studies to principles

RE Halbeisen, A Galgano, T Scherrer… - Cellular and molecular life …, 2008 - Springer
Post-transcriptional regulation of gene expression plays important roles in diverse cellular
processes such as development, metabolism and cancer progression. Whereas many …

The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript

E Ramirez‐Peña, J Treviño, Z Liu… - Molecular …, 2010 - Wiley Online Library
Small RNA molecules play key regulatory roles in many bacterial species. However, little
mechanistic data exists for the action of small regulatory RNAs in the human pathogen …

Shuttle expression plasmids for genetic studies in Streptococcus mutans

I Biswas, JK Jha, N Fromm - Microbiology, 2008 - microbiologyresearch.org
A set of shuttle plasmids containing four different constitutive promoters was generated to
facilitate overexpression of foreign and native genes in streptococci, such as Streptococcus …

Antisense RNA protects mRNA from RNase E degradation by RNA–RNA duplex formation during phage infection

D Stazic, D Lindell, C Steglich - Nucleic acids research, 2011 - academic.oup.com
The ecologically important cyanobacterium Prochlorococcus possesses the smallest
genome among oxyphototrophs, with a reduced suite of protein regulators and a …

Immunomodulating Enzymes from Streptococcus pyogenes—In Pathogenesis, as Biotechnological Tools, and as Biological Drugs

L Happonen, M Collin - Microorganisms, 2024 - mdpi.com
Streptococcus pyogenes, or Group A Streptococcus, is an exclusively human pathogen that
causes a wide variety of diseases ranging from mild throat and skin infections to severe …

Short RNA half-lives in the slow-growing marine cyanobacterium Prochlorococcus

C Steglich, D Lindell, M Futschik, T Rector, R Steen… - Genome biology, 2010 - Springer
Background RNA turnover plays an important role in the gene regulation of microorganisms
and influences their speed of acclimation to environmental changes. We investigated whole …

Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter

MKD Rodrigo, A Saiganesh, AJ Hayes… - Nature …, 2022 - nature.com
Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of
antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here …

Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection

J Richter, MM Monteleone, AJ Cork… - … and Cell Biology, 2021 - Wiley Online Library
Abstract Group A Streptococcus (GAS) is a Gram‐positive bacterial pathogen that causes an
array of infectious diseases in humans. Accumulating clinical evidence suggests that …

Virulence Gene Regulation by CvfA, a Putative RNase: the CvfA-Enolase Complex in Streptococcus pyogenes Links Nutritional Stress, Growth-Phase Control, and …

SO Kang, MG Caparon, KH Cho - Infection and immunity, 2010 - Am Soc Microbiol
Streptococcus pyogenes, a multiple-auxotrophic human pathogen, regulates virulence gene
expression according to nutritional availability during various stages in the infection process …