Background Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse
drug reaction that can lead to devastating thromboembolic complications, including …

Heparin-induced thrombocytopenia (HIT) is characterized clinically by thrombocytopenia,
hypercoagulability, and increased thrombosis risk, and serologically by platelet-activating …

Background Heparin-induced thrombocytopenia, defined by the presence of heparin-
dependent IgG antibodies, typically occurs five or more days after the start of heparin …

Introduction: Heparin-induced thrombocytopenia (HIT) is known for its strong association
with thrombosis and distinct pathogenesis involving anti-PF4/polyanion antibodies that …

Background Heparin-induced thrombocytopenia is a relatively common antibody-mediated
drug reaction. We studied the temporal relation between previous or current heparin therapy …

PURPOSE: To determine the sites of thromboses (venous versus arterial circulation) that
complicate the clinical course of immune-mediated heparin-induced thrombocytopenia, and …

Purpose Over the past 20 years results of clinical trials have provided information that has
revolutionized the approach to management of venous thromboembolic disease. New …

The frequency of immune heparin-induced thrombocytopenia (HIT) varies among
prospective studies. It is unknown whether this is caused by differences in the heparin …

Heparin-induced thrombocytopenia (HIT) is a potentially devastating immune mediated
adverse drug reaction caused by the emergence of antibodies that activate platelets in the …

Heparin is the anticoagulant of choice when a rapid anticoagulant effect is required because
its onset of action is immediate when administered by IV injection. Heparin is administered …