Chronic anemia is more prevalent in people living with HIV (PLWH) compared to the general
population. The mechanisms that drive chronic anemia in HIV are multifaceted and include …

The number of deaths related to cardiovascular disease is increasing every year, despite all
available therapies and the aggressive campaigns for lifestyle modification and prevention …

Exacerbated and persistent innate immune response marked by pro-inflammatory cytokine
expression is thought to be a major driver of chronic COVID-19 pathology. Although …

N 6-methyladenosine (m6A) is a prevalent RNA modification that plays a key role in
regulating eukaryotic cellular mRNA functions. RNA m6A modification is regulated by two …

RNA modification is considered as an epigenetic modification that plays an indispensable
role in biological processes such as gene expression and genome editing without altering …

ABSTRACT HIV-1 replicates in cells that express a wide array of innate immune sensors
and may do so simultaneously with other pathogens. How a coexisting innate immune …

We have recently demonstrated that long-term exposure of cigarette smoke condensate
(CSC) to HIV-uninfected (U937) and-infected (U1) macrophages induce packaging of pro …

Although combination antiretroviral therapy is extremely effective in lowering HIV RNA to
undetectable levels in the blood, HIV persists in latently infected CD4+ T-cells and …

Macrophages are the first line of defence against invading pathogens. They play a crucial
role in immunity but also in regeneration and homeostasis. Their remarkable plasticity in …

Although cells of the myeloid lineages, including tissue macrophages and conventional
dendritic cells, were rapidly recognized, in addition to CD4+ T lymphocytes, as target cells of …