Autophagy and endocrine resistance in breast cancer
The American Cancer Society estimates that over 200,000 new breast cancer cases are
diagnosed annually in the USA alone. Of these cases, the majority are invasive breast …
diagnosed annually in the USA alone. Of these cases, the majority are invasive breast …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Autophagy provides a conceptual therapeutic framework for bone metastasis from prostate cancer
YZ Wang, N Wu, N Jiang - Cell Death & Disease, 2021 - nature.com
Prostate cancer is a common malignant tumor, which can spread to multiple organs in the
body. Metastatic disease is the dominant reason of death for patients with prostate cancer …
body. Metastatic disease is the dominant reason of death for patients with prostate cancer …
Lipid nanocarriers of a lipid-conjugated estrogenic derivative inhibit tumor growth and enhance cisplatin activity against triple-negative breast cancer: pharmacokinetic …
T Andey, G Sudhakar, S Marepally, A Patel… - Molecular …, 2015 - ACS Publications
Breast cancer is the leading cause of malignancies among women globally. The triple
negative breast cancer (TNBC) subtype is the most difficult to treat and accounts for 15% of …
negative breast cancer (TNBC) subtype is the most difficult to treat and accounts for 15% of …
[PDF][PDF] Permanently Charged Cationic Lipids—Evolution from Excipients to Therapeutic Lipids
S Pushpa Ragini, R Banerjee, CJ Drummond… - Small Science, 2024 - d-nb.info
Complex diseases such as cancer and microbial infections are multifactorial in nature with
numerous redundant signalling pathways involved in the disease development.[1–3] …
numerous redundant signalling pathways involved in the disease development.[1–3] …
LncRNA PRKCQ‐AS1 regulates paclitaxel resistance in triple‐negative breast cancer cells through miR‐361‐5p/PIK3C3 mediated autophagy
S Zheng, W Fu, Q Huang, J Zhou, K Lu… - Clinical and …, 2023 - Wiley Online Library
Paclitaxel (PTX) resistance is a key cause of chemotherapy failure in patients with triple
negative breast cancer (TNBC). The aim of this study is to investigate the effect and …
negative breast cancer (TNBC). The aim of this study is to investigate the effect and …
Targeting steroid hormone receptors for anti‐cancer therapy—a review on small molecules and nanotherapeutic approaches
N Mahadik, D Bhattacharya… - Wiley …, 2022 - Wiley Online Library
The steroid hormone receptors (SHRs) among nuclear hormone receptors (NHRs) are
steroid ligand‐dependent transcription factors that play important roles in the regulation of …
steroid ligand‐dependent transcription factors that play important roles in the regulation of …
Progesterone-cationic lipid conjugate-based self-aggregates for cancer cell-selective uptake through macropinocytosis and the antitumour effect
Progesterone (PR) is an endogenous steroid hormone that activates the progesterone
receptor (PgR) and is known to play a critical role in cancer progression. Herein, we report …
receptor (PgR) and is known to play a critical role in cancer progression. Herein, we report …
Design, synthesis, and mechanistic investigations of bile acid–tamoxifen conjugates for breast cancer therapy
We have synthesized two series of bile acid tamoxifen conjugates using three bile acids
lithocholic acid (LCA), deoxycholic acid (DCA), and cholic acid (CA). These bile acid …
lithocholic acid (LCA), deoxycholic acid (DCA), and cholic acid (CA). These bile acid …
Development of liposomal formulation for delivering anticancer drug to breast cancer stem-cell-like cells and its pharmacokinetics in an animal model
The objective of the present study is to develop a liposomal formulation for delivering
anticancer drug to breast cancer stem-cell-like cells, ANV-1, and evaluate its …
anticancer drug to breast cancer stem-cell-like cells, ANV-1, and evaluate its …