[HTML][HTML] Molecular principles of metastasis: a hallmark of cancer revisited

J Fares, MY Fares, HH Khachfe, HA Salhab… - Signal transduction and …, 2020 - nature.com
Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-
related deaths. Yet, it remains poorly understood. The continuous evolution of cancer …

[HTML][HTML] Tetraspanins in extracellular vesicle formation and function

Z Andreu, M Yáñez-Mó - Frontiers in immunology, 2014 - frontiersin.org
Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

NONCODEV5: a comprehensive annotation database for long non-coding RNAs

SS Fang, LL Zhang, JC Guo, YW Niu, Y Wu… - Nucleic acids …, 2018 - academic.oup.com
Abstract NONCODE (http://www. bioinfo. org/noncode/) is a systematic database that is
dedicated to presenting the most complete collection and annotation of non-coding RNAs …

[HTML][HTML] Exosomes: A potential tool for immunotherapy of ovarian cancer

X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …

Exosomal miRNAs as cancer biomarkers and therapeutic targets

A Thind, C Wilson - Journal of extracellular vesicles, 2016 - Taylor & Francis
Intercommunication between cancer cells and with their surrounding and distant
environments is key to the survival, progression and metastasis of the tumour. Exosomes …

Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo

D Zhang, H Lee, Z Zhu… - American Journal of …, 2017 - journals.physiology.org
Exosomes are nanovesicles secreted by cells and contain various molecules including
protein, lipid, and DNA/RNA. They are crucial mediators of the intercellular communication …

Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy

F Vakhshiteh, F Atyabi, SN Ostad - International journal of …, 2019 - Taylor & Francis
Mesenchymal stem cells (MSCs) are multipotent stromal cells present in various adult
tissues. Several studies suggest that MSCs secrete exosomes that perform as mediators in …

Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer

I Lazar, E Clement, S Dauvillier, D Milhas… - Cancer research, 2016 - AACR
Malignant progression results from a dynamic cross-talk between stromal and cancer cells.
Recent evidence suggests that this cross-talk is mediated to a significant extent by …

Development and MPI tracking of novel hypoxia-targeted theranostic exosomes

KO Jung, H Jo, JH Yu, SS Gambhir, G Pratx - Biomaterials, 2018 - Elsevier
Treating the hypoxic region of the tumor remains a significant challenge. The goals of this
study are to develop an exosome platform that can target regions of tumor hypoxia and that …

Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions

DW Greening, HPT Nguyen, K Elgass… - Biology of …, 2016 - academic.oup.com
Embryo implantation into receptive endometrium requires synergistic endometrial-blastocyst
interactions within the uterine cavity and is essential for establishing pregnancy. We …