FTO m6A demethylase in obesity and cancer: implications and underlying molecular mechanisms
Fat mass and obesity-associated protein (FTO) is the first reported RNA N6-
methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most …
methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most …
Modelling metabolic diseases and drug response using stem cells and organoids
Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a
major threat to health in the modern world, but efforts to understand the underlying …
major threat to health in the modern world, but efforts to understand the underlying …
Organoids: The current status and biomedical applications
S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
Regulatory mechanisms of the early phase of white adipocyte differentiation: An overview
M Audano, S Pedretti, D Caruso, M Crestani… - Cellular and molecular …, 2022 - Springer
The adipose organ comprises two main fat depots termed white and brown adipose tissues.
Adipogenesis is a process leading to newly differentiated adipocytes starting from precursor …
Adipogenesis is a process leading to newly differentiated adipocytes starting from precursor …
The use of stem cell-derived organoids in disease modeling: an update
Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …
during the past decade. They are three-dimensional in vitro culturing models that originate …
[HTML][HTML] Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications
S Sharma, S Muthu, M Jeyaraman… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
With developments in the field of tissue engineering and regenerative medicine, the use of
biological products for the treatment of various disorders has come into the limelight among …
biological products for the treatment of various disorders has come into the limelight among …
Optical diffraction tomography and Raman spectroscopy reveal distinct cellular phenotypes during white and brown adipocyte differentiation
White adipose tissue (WAT) and brown adipose tissue (BAT) are the primary types of fats in
humans, and they play prominent roles in energy storage and thermogenesis, respectively …
humans, and they play prominent roles in energy storage and thermogenesis, respectively …
Secreted frizzled related proteins in cardiovascular and metabolic diseases
H Guan, J Zhang, J Luan, H Xu, Z Huang… - Frontiers in …, 2021 - frontiersin.org
Abnormal gene expression and secreted protein levels are accompanied by extensive
pathological changes. Secreted frizzled related protein (SFRP) family members are …
pathological changes. Secreted frizzled related protein (SFRP) family members are …
Autologous human immunocompetent white adipose tissue‐on‐chip
J Rogal, J Roosz, C Teufel, M Cipriano, R Xu… - Advanced …, 2022 - Wiley Online Library
Obesity and associated diseases, such as diabetes, have reached epidemic proportions
globally. In this era of “diabesity”, white adipose tissue (WAT) has become a target of high …
globally. In this era of “diabesity”, white adipose tissue (WAT) has become a target of high …
The inflammatory profile of obesity and the role on pulmonary bacterial and viral infections
Obesity is a globally increasing health problem, entailing diverse comorbidities such as
infectious diseases. An obese weight status has marked effects on lung function that can be …
infectious diseases. An obese weight status has marked effects on lung function that can be …