Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] Mechanical basis of bone strength: influence of bone material, bone structure and muscle action

NH Hart, S Nimphius, T Rantalainen… - … of musculoskeletal & …, 2017 - ncbi.nlm.nih.gov
This review summarises current understanding of how bone is sculpted through adaptive
processes, designed to meet the mechanical challenges it faces in everyday life and athletic …

Adaptations to endurance and strength training

DC Hughes, S Ellefsen, K Baar - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
The capacity for human exercise performance can be enhanced with prolonged exercise
training, whether it is endurance-or strength-based. The ability to adapt through exercise …

The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis

F Damas, CA Libardi, C Ugrinowitsch - European journal of applied …, 2018 - Springer
Resistance training (RT)-induced skeletal muscle hypertrophy is a highly intricate process.
Despite substantial advances, we are far from understanding exactly how muscle …

Periodization and block periodization in sports: emphasis on strength-power training—a provocative and challenging narrative

MH Stone, WG Hornsby, GG Haff, AC Fry… - The Journal of …, 2021 - journals.lww.com
Abstract Stone, MH, Hornsby, WG, Haff, GG, Fry, AC, Suarez, DG, Liu, J, Gonzalez-Rave, JM,
and Pierce, KC. Periodization and block periodization in sports: emphasis on strength-power …

Longer interset rest periods enhance muscle strength and hypertrophy in resistance-trained men

BJ Schoenfeld, ZK Pope, FM Benik… - The journal of …, 2016 - journals.lww.com
Abstract Schoenfeld, BJ, Pope, ZK, Benik, FM, Hester, GM, Sellers, J, Nooner, JL, Schnaiter,
JA, Bond-Williams, KE, Carter, AS, Ross, CL, Just, BL, Henselmans, M, and Krieger, JW …

Greater neural adaptations following high-vs. low-load resistance training

NDM Jenkins, AA Miramonti, EC Hill, CM Smith… - Frontiers in …, 2017 - frontiersin.org
We examined the neuromuscular adaptations following 3 and 6 weeks of 80 vs. 30% one
repetition maximum (1RM) resistance training to failure in the leg extensors. Twenty-six men …

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide‐derived measures of muscle …

MS Brook, DJ Wilkinson, WK Mitchell… - The FASEB …, 2015 - Wiley Online Library
Resistance exercise training (RET) is widely used to increase muscle mass in athletes and
also aged/cachectic populations. However, the time course and metabolic and molecular …

Early resistance training-induced increases in muscle cross-sectional area are concomitant with edema-induced muscle swelling

F Damas, SM Phillips, ME Lixandrão, FC Vechin… - European journal of …, 2016 - Springer
Purpose It has been proposed that skeletal muscle shows signs of resistance training (RT)-
induced muscle hypertrophy much earlier (ie,~ 3–4 weeks of RT) than previously thought …

Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli

KM Wisdom, SL Delp, E Kuhl - Biomechanics and modeling in …, 2015 - Springer
Skeletal muscle undergoes continuous turnover to adapt to changes in its mechanical
environment. Overload increases muscle mass, whereas underload decreases muscle …