Cancer/testis antigens: expression, regulation, tumor invasion, and use in immunotherapy of cancers
A Salmaninejad, MR Zamani… - Immunological …, 2016 - Taylor & Francis
Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling
A Dema, E Perets, MS Schulz, VA Deák, E Klussmann - Cellular signalling, 2015 - Elsevier
The second messenger cyclic adenosine monophosphate (cAMP) can bind and activate
protein kinase A (PKA). The cAMP/PKA system is ubiquitous and involved in a wide array of …
protein kinase A (PKA). The cAMP/PKA system is ubiquitous and involved in a wide array of …
A photonic platform for donor spin qubits in silicon
Donor spins in silicon are highly competitive qubits for upcoming quantum technologies,
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …
Immune therapeutics in the treatment of advanced gastric and esophageal cancer
Systemic chemotherapy is the mainstay of therapy in patients with advanced gastric and
esophageal cancer, but has multiple drawbacks including lack of durable efficacy and dose …
esophageal cancer, but has multiple drawbacks including lack of durable efficacy and dose …
Trial watch: dendritic cell-based anticancer therapy
The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …
immune responses in cancer patients has been extensively investigated throughout the past …
[HTML][HTML] Heat shock protein 70–2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth
N Jagadish, D Parashar, N Gupta, S Agarwal, V Suri… - BMC cancer, 2016 - Springer
Background Colorectal cancer (CRC) is the third leading cause of cancer related deaths
worldwide both in men and women. Our recent studies have indicated an association of heat …
worldwide both in men and women. Our recent studies have indicated an association of heat …
[HTML][HTML] A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer
N Jagadish, D Parashar, N Gupta, S Agarwal… - Journal of Experimental …, 2015 - Springer
Background Colorectal cancer (CRC) ranks third among the estimated cancer cases and
cancer related mortalities in the Western world. Early detection and efficient therapy of CRC …
cancer related mortalities in the Western world. Early detection and efficient therapy of CRC …
ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic …
S Nadaraja, D Schledermann, J Herrstedt… - Acta …, 2020 - Taylor & Francis
Background: Little is known about the biological factors influencing ovarian cancer (OC)
patient outcome, especially in older patients who are often underrepresented in clinical …
patient outcome, especially in older patients who are often underrepresented in clinical …
[HTML][HTML] Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer
N Gupta, N Jagadish, A Surolia… - American journal of cancer …, 2017 - ncbi.nlm.nih.gov
Abstract Heat shock protein 70-2 (HSP70-2) is known to be involved in tumor progression.
However, its molecular role and mechanism in epithelial ovarian cancer (EOC) remains …
However, its molecular role and mechanism in epithelial ovarian cancer (EOC) remains …
Targeting the testis-specific heat-shock protein 70-2 (HSP70-2) reduces cellular growth, migration, and invasion in renal cell carcinoma cells
S Singh, A Suri - Tumor Biology, 2014 - Springer
Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiotherapy and
chemotherapy. Current therapies for the RCC patients are limited owing to lack of diagnosis …
chemotherapy. Current therapies for the RCC patients are limited owing to lack of diagnosis …