Cancer/testis antigens: expression, regulation, tumor invasion, and use in immunotherapy of cancers

A Salmaninejad, MR Zamani… - Immunological …, 2016 - Taylor & Francis
Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …

Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling

A Dema, E Perets, MS Schulz, VA Deák, E Klussmann - Cellular signalling, 2015 - Elsevier
The second messenger cyclic adenosine monophosphate (cAMP) can bind and activate
protein kinase A (PKA). The cAMP/PKA system is ubiquitous and involved in a wide array of …

A photonic platform for donor spin qubits in silicon

KJ Morse, RJS Abraham, A DeAbreu, C Bowness… - Science …, 2017 - science.org
Donor spins in silicon are highly competitive qubits for upcoming quantum technologies,
offering complementary metal-oxide semiconductor compatibility, coherence (T 2) times of …

Immune therapeutics in the treatment of advanced gastric and esophageal cancer

R Park, S Williamson, A Kasi, A Saeed - Anticancer Research, 2018 - ar.iiarjournals.org
Systemic chemotherapy is the mainstay of therapy in patients with advanced gastric and
esophageal cancer, but has multiple drawbacks including lack of durable efficacy and dose …

Trial watch: dendritic cell-based anticancer therapy

N Bloy, J Pol, F Aranda, A Eggermont, I Cremer… - …, 2014 - Taylor & Francis
The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …

[HTML][HTML] Heat shock protein 70–2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth

N Jagadish, D Parashar, N Gupta, S Agarwal, V Suri… - BMC cancer, 2016 - Springer
Background Colorectal cancer (CRC) is the third leading cause of cancer related deaths
worldwide both in men and women. Our recent studies have indicated an association of heat …

[HTML][HTML] A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer

N Jagadish, D Parashar, N Gupta, S Agarwal… - Journal of Experimental …, 2015 - Springer
Background Colorectal cancer (CRC) ranks third among the estimated cancer cases and
cancer related mortalities in the Western world. Early detection and efficient therapy of CRC …

ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic …

S Nadaraja, D Schledermann, J Herrstedt… - Acta …, 2020 - Taylor & Francis
Background: Little is known about the biological factors influencing ovarian cancer (OC)
patient outcome, especially in older patients who are often underrepresented in clinical …

[HTML][HTML] Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer

N Gupta, N Jagadish, A Surolia… - American journal of cancer …, 2017 - ncbi.nlm.nih.gov
Abstract Heat shock protein 70-2 (HSP70-2) is known to be involved in tumor progression.
However, its molecular role and mechanism in epithelial ovarian cancer (EOC) remains …

Targeting the testis-specific heat-shock protein 70-2 (HSP70-2) reduces cellular growth, migration, and invasion in renal cell carcinoma cells

S Singh, A Suri - Tumor Biology, 2014 - Springer
Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiotherapy and
chemotherapy. Current therapies for the RCC patients are limited owing to lack of diagnosis …