Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

Major psychiatric disorders are heritable but they are genetically complex. This means that,
with certain exceptions, single gene markers will not be helpful for diagnosis. However, we …

Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic
predisposition to rosacea is suggested by existing evidence, the genetic basis remains …

Many neuropsychiatric disorders exhibit differences in prevalence, age of onset, symptoms
or course of illness between males and females. For the most part, the origins of these …

While genomic data is frequently collected under distinct research protocols and disparate
clinical and research regimes, there is a benefit in streamlining sequencing strategies to …

Genome-wide (GWAS) and copy number variant (CNV) association studies have
reproducibly identified numerous risk alleles associated with bipolar disorder (BD), major …

Human-induced pluripotent stem cells (hiPSCs) allow for the establishment of brain cellular
models of psychiatric disorders that account for a patient's genetic background. Here, we …

Aim Severe mental illnesses (SMI), such as bipolar disorder and schizophrenia, are highly
heritable, and have a complex pattern of inheritance. Genome‐wide association studies …

An increasing body of evidence suggests that impaired synapse development and function
are associated with schizophrenia; however, the underlying molecular pathophysiological …

An anxious or inhibited temperament (IT) early in life is a major risk factor for the later
development of stress-related psychopathology. Starting in infancy, nonhuman primates, like …