[HTML][HTML] The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

[HTML][HTML] Immune response to dengue and Zika

A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Mosquito vector competence for dengue is modulated by insect-specific viruses

RP Olmo, YMH Todjro, ERGR Aguiar… - Nature …, 2023 - nature.com
Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV)
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …

[HTML][HTML] SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

D Olagnier, E Farahani, J Thyrsted… - Nature …, 2020 - nature.com
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we …

Field-deployable viral diagnostics using CRISPR-Cas13

C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh… - Science, 2018 - science.org
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

[HTML][HTML] Pathogenesis of Zika virus infection

MI Giraldo, M Gonzalez-Orozco… - Annual Review of …, 2023 - annualreviews.org
Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

[HTML][HTML] Chloroquine, an endocytosis blocking agent, inhibits Zika virus infection in different cell models

R Delvecchio, LM Higa, P Pezzuto, AL Valadão… - Viruses, 2016 - mdpi.com
Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …

Zika virus has oncolytic activity against glioblastoma stem cells

Z Zhu, MJ Gorman, LD McKenzie, JN Chai… - Journal of Experimental …, 2017 - rupress.org
Glioblastoma is a highly lethal brain cancer that frequently recurs in proximity to the original
resection cavity. We explored the use of oncolytic virus therapy against glioblastoma with …

Zika virus replication in the mosquito Culex quinquefasciatus in Brazil

DRD Guedes, MHS Paiva, MMA Donato… - Emerging microbes & …, 2017 - Taylor & Francis
Zika virus (ZIKV) is a flavivirus that has recently been associated with an increased
incidence of neonatal microcephaly and other neurological disorders. The virus is primarily …

[HTML][HTML] Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes

PF Ledur, K Karmirian, CSG Pedrosa, LRQ Souza… - Scientific reports, 2020 - nature.com
Zika virus (ZIKV) has been extensively studied since it was linked to congenital
malformations, and recent research has revealed that astrocytes are targets of ZIKV …