Salivary cortisol (sCort) and salivary alpha-amylase (sAA) constitute proxy measures of the
two major stress response systems, ie the hypothalamic-pituitary-adrenal axis and the …

Publications relating parotid dose–volume characteristics to radiotherapy-induced salivary
toxicity were reviewed. Late salivary dysfunction has been correlated to the mean parotid …

Purpose This systematic review aimed to assess the literature for prevalence, severity, and
impact on quality of life of salivary gland hypofunction and xerostomia induced by cancer …

Background and purpose Intensity-modulated radiation therapy (IMRT) provides the
possibility of dose-escalation with better normal tissue sparing. This study was performed to …

Purpose: To compare directly the effect of intensity-modulated radiotherapy (IMRT) vs.
conventional radiotherapy (CRT) on salivary flow and quality of life (QoL) in patients with …

Purpose This randomized trial compared the rates of delayed xerostomia between two-
dimensional radiation therapy (2DRT) and intensity-modulated radiation therapy (IMRT) in …

A dry mouth or xerostomia is one of the most common complications during and after
radiotherapy for head and neck cancer, because irreparable damage is caused to the …

Modern advances in computers have fueled parallel advances in imaging technologies. The
improvements in imaging have in turn allowed a higher level of complexity to be …

Background About 10 000 persons are diagnosed as having carcinoma of the oral cavity or
the throat in Germany every year. Squamous-cell carcinoma accounts for 95% of cases …

PURPOSE: To evaluate the efficacy of using intensity-modulated radiotherapy (IMRT) in the
primary treatment of nasopharyngeal carcinoma (NPC), including the role of dose escalation …