Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis

S Spahis, E Delvin, JM Borys, E Levy - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …

Nonalcoholic fatty liver disease in children

JP Mann, L Valenti, E Scorletti… - Seminars in liver …, 2018 - thieme-connect.com
Nonalcoholic steatohepatitis, a progressive form of nonalcoholic fatty liver disease (NAFLD),
is one of the most common hepatic diseases in children who present with particular risk …

Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity

SE Hampl, SG Hassink, AC Skinner, SC Armstrong… - …, 2023 - publications.aap.org
You have in your hands, or at your fingertips, the first edition of the American Academy of
Pediatrics clinical practice guideline for evaluation and management of children and …

NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children: recommendations from the Expert Committee on …

MB Vos, SH Abrams, SE Barlow, S Caprio… - Journal of pediatric …, 2017 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease that
occurs in the setting of insulin resistance and increased adiposity. It has rapidly evolved into …

[PDF][PDF] Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: a systematic review and network meta‐analysis

S Singh, R Khera, AM Allen, MH Murad… - Hepatology, 2015 - Wiley Online Library
We performed a Bayesian network meta‐analysis combining direct and indirect treatment
comparisons to assess the comparative effectiveness of pharmacological agents for the …

S-adenosylmethionine: From the discovery of its inhibition of tumorigenesis to its use as a therapeutic agent

RM Pascale, MM Simile, DF Calvisi, CF Feo, F Feo - Cells, 2022 - mdpi.com
Alterations of methionine cycle in steatohepatitis, cirrhosis, and hepatocellular carcinoma
induce MAT1A decrease and MAT2A increase expressions with the consequent decrease of …

[PDF][PDF] Appraisal of clinical care practices for child obesity treatment. Part I: interventions

AC Skinner, AE Staiano, SC Armstrong, SL Barkin… - …, 2023 - edu.endocrincentr.ru
The objective of this technical report is to provide clinicians with evidence-based, actionable
information upon which to make assessment and treatment decisions for children and …

Metformin, pioglitazone, dapagliflozin and their combinations ameliorate manifestations associated with NAFLD in rats via anti-inflammatory, anti-fibrotic, anti-oxidant …

HH Shaaban, I Alzaim, A El-Mallah, RG Aly… - Life Sciences, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is an important health threat that is strongly linked
to components of metabolic syndrome, particularly the low-grade inflammatory changes …

Metformin: the hidden chronicles of a magic drug

K Mahmood, M Naeem, NA Rahimnajjad - European journal of internal …, 2013 - Elsevier
Metformin, a biguanide is well known treatment for type 2 diabetes mellitus that has diverse
mechanism of actions. Various studies have elucidated the role of this drug in different …

[HTML][HTML] Recent advances in dietary supplementation, in treating non-alcoholic fatty liver disease

T Eslamparast, S Eghtesad, H Poustchi… - World journal of …, 2015 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is currently known as the most common liver
problem, characterized by excessive lipid accumulation in hepatocytes, which may progress …